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DAVID G. HICKS(美国)
作者:DAVID G. HICKS 更新:2009年1月2日  浏览:80193 [字体: ]
 

DAVID G. HICKS博士:     

 

1957116日出生于美国纽约Albion

 

教育经历:

 

            1975-79                     生物学学士,纽约布法罗Canisius学院

 

1979-84                    医学博士,纽约Rochester大学医学与牙医学学院

 

毕业后培训:

      

1984-85                       实习医师,费城宾夕法尼亚大学医院医学部

 

1985-89                      住院医师,费城宾夕法尼亚大学医院病理学与实验医学部

 

学术任命:

      

1990-96                     病理助理教授,纽约Rochester大学医学院

 

1990-96                      整形外科助理教授,纽约Rochester大学医学院

 

1996-99                      病理与实验医学部副教授,纽约Rochester大学医学院

      

1996-99                       整形外科副教授,纽约Rochester大学医学院

 

             1997-99                      肿瘤学副教授,纽约Rochester大学医学院

 

2005-07                       肿瘤学与病理学教授,纽约布法罗Roswell Park肿瘤研究所

 

2007-                           病理与实验医学部教授,纽约Rochester大学医学院

 

行政:

 

外科病理学主管, Cleveland临床基金会

解剖病理学主任, Roswell Park肿瘤研究所

外科病理学主任, Rochester大学医学中心

 

 

术团职务和社会兼:

 

美加病理学学会United States and Canadian Academy of Pathology

美国东部肿瘤协作组(肉瘤委员会病理学主席)

美国病理医师学会SAM委员会副主席

美国生物染色委员会当选成员

 

编委会:

 

Archive of Pathology and Laboratory Medicine, 编委

Journal of Bone and Joint Surgery, 编委

Biotechnic & Histochemistry, 编委

Cancer, 特别审稿人

American Journal of Pathology, 特别审稿人

Clinical Cancer Research, 特别审稿人

Breast Cancer Research, 特别审稿人

 

DAVID G. HICKS博士获得二十多项资金资助,发表上百篇文章与综述,参与多本书籍编辑,在美国全国会议发表许多摘要,并受邀在许多大会上做演讲。

 







                                  CURRICULUM VITAE
                                  DAVID G. HICKS, M.D.
 
 
Home Address:              6 Marvin Park
                            Rochester, New York 14610
 
Office Address:              Department of Pathology and Laboratory Medicine
                            University of Rochester Medical Center
                            601 Elmwood Avenue, Box 626
                            Rochester New York,
                            585-276-4246
 
Date of Birth:           January 16, 1957
 
Place of Birth:         Albion, New York
 
Education:
 
       1975-79              B.A. (Biology), Canisius College of Buffalo, Buffalo, New York
 
1979-84                      M.D. (With Honor and Distinction)
University of Rochester School of Medicine and Dentistry, Rochester, New York
                                                                                                 
Awards, Honors and Fellowships:
 
       1981-82              Medical Student Fellowship, Department of Pathology,
                            University of Rochester, Rochester, New York
      
1984                     Member, Alpha Omega Alpha Honor Medical Society
      
1984                     Robert Katz A ward for Clinical Research Excellence,
                            University of Rochester School of Medicine &
                            Dentistry
      
1984                     Award in Honor of George H. Whipple, M.D., presented by
                            The Rochester Academy of Medicine
      
1989                     Stowell-Orbison Award, United States and Canadian
                            Academy of Pathology
      
1991                     Arthur Purdy Stout Award, United States and Canadian
                            Academy of Pathology
      
1993                     Certificate of Commendation for excellence in medical
                            student teaching, second year class, 1992-93
      
1995                     Kappa Delta Elizabeth Winston Lanier Award for
Outstanding Orthopaedic Research, American Academy of Orthopaedic Surgeons
      
1996                     Andrew W. Mellon Dean's Teaching Scholar, 1996-1999
 
1997                     Duthie-Evarts Resident Education Award presented by the
                            Department of Orthopaedics
 
2002                      John Beach Hazard Distinguished Teaching Award, presented by
Cleveland Clinic Foundation, Department of Pathology and
Laboratory Medicine.
 
2006                            Dr. Edith E. Sproul Teaching Award, presented by Roswell Park Cancer Institute, Department of Pathology and Laboratory Medicine
 
Postgraduate Training:
      
1984-85         Intern, Department of Medicine, Hospital of the University
                            of Pennsylvania, Philadelphia, PA
      
1985-89                      Resident, Department of Pathology and Laboratory Medicine, Hospital of the University of Pennsylvania, Philadelphia, PA
 
Academic Appointments:
      
1984-85                      Assistant Instructor, Department of Medicine, University of Pennsylvania School of Medicine, Philadelphia, Pennsylvania
      
1985-89                      Assistant Instructor, Department of Pathology and Laboratory Medicine, University of Pennsylvania School of Medicine, Philadelphia, PA
      
1989-90                      Lecturer, Department of Pathology and Laboratory Medicine, University of Pennsylvania School of Medicine, Philadelphia, PA
      
1989-96                      Instructor, Orthopedic Pathology Review Course, Harry Schwamm, M.D., Course Director, Atlantic City, NJ and Newport Beach, CA
 
1990-96         Assistant Professor, Department of Pathology (primary),
University of Rochester School of Medicine, Rochester, NY
 
1990-96                      Assistant Professor, Department of Orthopaedics (secondary), University of Rochester School of Medicine, Rochester, NY
 
1996-99                      Associate Professor, Department of Pathology and Laboratory Medicine (primary clinician/scientist tract) University of Rochester School of Medicine, Rochester, NY
      
1996-99                       Associate Professor, Department of Orthopaedics (secondary), University of Rochester School of Medicine, Rochester, NY
 
       1997-99        Associate Professor of Oncology (secondary), University
                            of Rochester School of Medicine, Rochester, NY
 
 
 
 
2005-07                       Professor of Oncology and Pathology, Roswell Park Cancer Institute, Buffalo, New York
 
2007-                           Professor of Pathology and Laboratory Medicine, University of Rochester School of Medicine, Rochester, New York
 
Hospital Appointments:
 
       1989-1990          Attending Staff
Hospital of the University of Pennsylvania, Philadelphia, PA
 
       1990-1999          Attending Staff
University of Rochester Medical Center, Rochester, NY
 
       1999-2001          Senior Staff Pathologist
Rochester General Hospital,Rochester, NY
 
       2001-2005           Staff Pathologist
Cleveland Clinic Foundation, Cleveland, OH
 
       2006-2007           Staff Pathologist
Roswell Park Cancer Institute, Buffalo, NY
 
       2007-Present             Attending Staff
University of Rochester Medical Center, Rochester, NY
 
Administrative Responsibilities:
 
Section Head, Surgical Pathology, Cleveland Clinic Foundation    
Director of Anatomic Pathology, Roswell Park Cancer Institute
Director of Surgical Pathology, University of Rochester Medical Center
 
Specialty Certification:
 
Diplomat, American Board of Pathology (Anatomic
Pathology, August 1990)
 
Licensure:
 
Pennsylvania #MD-035357-E
New York #183009-1
Ohio #80071
 
Membership in Professional and Scientific Societies:
 
United States and Canadian Academy of Pathology
Eastern Cooperative Oncology Group (Pathology Chairman For Sarcoma Committee)
College of American Pathologists, SAM Committee Vice Chairman
Biological Stain Commission, Elected Trustee
 
 
 
 
Editorial Boards:
 
Archive of Pathology and Laboratory Medicine, Editorial Board
Journal of Bone and Joint Surgery, Editorial Board
Biotechnic & Histochemistry, Editorial Board
Cancer, Ad Hoc reviewer
American Journal of Pathology, Ad Hoc reviewer
Clinical Cancer Research, Ad Hoc reviewer
Breast Cancer Research, Ad Hoc reviewer
 
Grant Support:
 
NIH, AR 40325
"Autocrine and Ionic Regulation of Chondrocyte Phenotype".  5/92-4/96. R.N. Rosier, PI, D.G. Hicks, co-I; $144,537/year
Bristol Meyers Squibb Zimmer, Orthopaedic Research and Education Foundation Institutional Award
"Molecular Pathology in Orthopaedics". 7/91-6/96. R.N. Rosier, PI, D.G. Hicks, co-I, J.E. Puzas, co-I; $50,000/year
Oral and Maxillofacial Surgery Foundation
"Correlation of Magnetic Resonance Images of the Bone Marrow of the Mandibular Condyle with Histologic Observations in Core Biopsies Obtained in Patients Undergoing TMJ Surgery". 3/92-3/94. P.L. Westesson, PI, D.G. Hicks, co-I; $35,000 .
NIH, BRSG, PHS57RR05403-30
"Growth factor and matrix protein expression in skeletal neoplasms". 7/91-6/92. D.G. Hicks, PI; $4,500/year
Arthroscopy Association of North America
"Chondrogenesis and osteogenesis in arthrofibrotic tissues of the knee". 4/92-3/93. W.J. Sebastianelli, PI, D.G. Hicks, co-I; $14,440/year
Eastman Dental Center
"In vitro and in vivo principles of site directed bone formation". 7/92-6/93. J.E.Puzas, PI. D.G. Hicks, co-I; $10,000/year
DePuy Inc
"In vitro and in vivo principles of site directed bone formation". 5/92-4/94. J.E. Puzas, PI. D.G. Hicks, co-I; $55,000/year
Buswell Fellowship
7/93-6/94. Awarded to DG Hicks; $10,000
NIH, R29ES07138-01
"Effects of lead on the epiphyseal growth plate". 7/95-11/00. D.G. Hicks, PI. $70,000/year
NIH CA 71603-0 I
Growth plate radiation response: mechanisms and therapy".  4/97-3/01. R.N. Ro~ter, PI. D.G. Hicks, co-I; $156,815/year.
NIH ES08121-O1
"The effect of lead on skeletal remodeling in vitro". 4/97-3/01. J.E. Puzas, PI. D.G. Hicks, co-I; $144,941/year
RPC 07384
"Molecular signatures predicting osseous metastases of breast carcinoma".  Active - 8/03 - 8/04.
RPC 07501
"Laryngeal Wound Healing: Optimization of vocal outcome in a canine model".  Active - 3/04 - 3/05.
RPC 07550
"In-Vivo analysis of glycosaminoglycan-based hydrogels for application in the field of Plastic and Reconstructive Surgery".  Active - 6/04 - 6/05
NIH(NIAMS)1P30AR500953
Cleveland Clinic Foundation Musculoskeletal Core Center Grant.  Active - 4/04-4/05, D.G. Hicks, Histology Core Consultant
AICR Grant
"Evaluation of the prognostic significance and functional role of fascin in colonic carcinoma".  Active - June/04-June/07.  Dr. Josephine Adams, Cell Biology, Lerner Research Institute - PI, D.G. Hicks, Consultant
Susan G. Komen Foundation Breast Cancer Grant
"The role of Toll-Like Receptors in Breast Cancer".  Active - 4/04-4/06, Dr. Joe DiDonato, Cancer Biology, Lerner Research Institute - PI, D.G. Hicks, Co-Investigator
NIHR01 AR46249
"Genetic basis of chondrogenesis" (Pending), Dr. Veronique Lefebvre, Lerner Research Institute - PI, D.G. Hicks, Collaborator
NIHR01 CA106415-01A1
"Inhibition of VEGF mediated angiogenesis by TIMP-3" (Pending), Dr. Bela Anand-Apte, Cole Eye Institute - PI, D.G. Hicks, Collaborator
NIH/NCI CA112882-01
“Biomarkers for the Progression of Head and Neck Squamous Cell Carcinoma”  D.G. Hicks, Co-Investigator, 4/2006-3/2010
Alpha Foundation Grant
“HER2 Positive Breast Cancer: Unde, rstanding the Clinical Diversity and Molecular Factors Affecting Herceptin Response in this Subset of Patients”.  DATES:  1/1/07 - 12/31/07, Drs Hicks and Kouhry Co-Principle Investigators, DIRECT BUDGET:  $76,844
NIH/NCCAM
“Flaxseed vs. Aromatase Inhibitors: Breast Tumor Characteristics and Prognosis” (1R21AT004024-21) Hicks, D.G., co-investigator, 5% effort.  5/01/2007 – 4/30/2010
NIH/NCI
“Dietary Lignan Effects on Hormone, Growth, and Signaling Factors in breast tumors.” (1R03CA128035-01A1)  Hicks, D.G., co-investigator, 3% effort.  12/01/2006 – 11/30/2009
 
 
 
 
 
 
 
 
 
 
Teaching Contributions:
 
* University of Rochester, School of Medicine Pathology Courses, second year class;
       General Pathology Course, second year class; Laboratory instructor, Fall 1990-1994
       Musculoskeletal system- Lectures on the pathology of bone tumors, the pathology of soft
       tissue tumors, normal joint function and physiology, and the pathology of arthritis.
       Spring 1991-2001
       Lymphoreticular system, Laboratory instructor, Spring 1991-2001
 
* Orthopaedic Pathology Elective
 
* Advisor for medical student and pathology residents research projects
 
* Weekly pathology teaching conference for Orthopaedic Surgery Residents, 1990-1999
 
* Weekly teaching conference for Pathology Residents, 1990-1999
 
 
Publications:
 
Original Peer Reviewed Papers:
 
1.        Bhandari AK. Nanda NC. Hicks DG: Two-dimensional echocardiography of intracardiac masses: Echo pattern-histopathology correlation. Ultrasound Med Biol. 1982;8(6):673-680.
 
2.        Perry IC. Nanda NC, Hicks DG. Harris IP: Two-dimensional echocardiographic identification of aortico-left ventricular tunnel. Am J Cardiol. 1983;52:913-914.
 
3.        Taves DR. Forbes N. Silverman D. Hicks DG: Inorganic fluoride concentrations in human and animal tissues. In: Fluorides: Effects on Vegetation. Animals and Humans. I.S. Shupe, H.B. Peterson. and N.C. Leon (eds.). Paragon Press. Inc., Salt Lake City, Utah, 1983.
 
4.        Brumback RA, Gerber IE, Hicks DG, Straucher IA: Adenocarcinoma of the stomach following irradiation and chemotherapy for lymphoma in young patients. Cancer. 1984;54:994-998.
 
5.        Hicks DG, Ohlsson-Wilhelm BM, Farley BA. Kosciolek BA. Rowley PT: K-562 cell erythroid differentiation: Requirement for a factor in fetal bovine serum. Exp Hematol. 1985;13:273-280.
 
6.        Remaley AT, Hicks DG, Shaw LM: Laboratory assessment of a carbamate based insecticide poisoning. Clin Chem. 1988;34(9):1933-1936.
 
7.        Hicks DG. LiVolsi VA. Neidich IA. Puck 1M. Kant IA: Clonal analysis of solitary follicular nodules in the thyroid. Am J Pathol. 1990;137:553-562. (winner of the 1991 Arthur Purdy Stout Award. Arthur Purdy Stout Society, United States and Canadian Academy of Pathology)
 
8.        Galetta SL. Stadtmauer EA. Hicks DG, Raps EC, Plock G, Oberholtzer IC. Reactive lymphohistiocytosis with recurrence in the optic chiasm. J Neuro-ophthalmol. 1991;11(1):25-30.
 
9.        Karpe M. Hicks DG, Torsian M. Colon invasion by primary splenic lymphoma: A case report and review of the literature. Surgery. 1992;111:224-227.
 
10.      Godyn II, Hicks DG, Hsu SH. Kant I, Montone KT, Zimijewski CM, Tomaszewski IE. Demonstration of passenger leukocytes in a case of Epstein Barr virus post transplant Iymphoproliferative disorder using restriction fragment length polymorphism analysis. Arch Pathol Lab Med. 1992;116:249-252.
 
11.      Montone KT, Friedman H. Hidinka R. Hicks DG, Kant JA, Tomaszewski IE. In situ hybridization for Epstein-Barr virus not I repeats in posttransplant lymphoproliferative disorder.  Mod Pathol. 1992;5:292-302.
 
12.       Macher D, Westesson PL, Brooks SL, Hicks DG, Tallents RH. Temporomandibular joint: surgically created disc displacement causes arthrosis in the rabbit. Oral Surg Oral Med Oral Pathol. 1992;73:645-649.
 
13.      Tomaszewski lE, Brooks JSJ, Hicks DG, LiVolsi VA: Diabetic mastopathy: A distinctive clinicopathologic entity. Hum Pathol. 1992;23:780-786.
 
14.      Crabb ID, Hughes SS, Hicks DG, Puzas IE, Rosier RN. Non-radioactive in situ hybridization using digoxigenin labeled oligonucleotides: applications to musculoskeletal tissues. Am J Pathol. 1992;141:579-589.
 
15.        Eriksson L, Westesson PL, Macher D, Hicks D, Tallents RH. Temporomandibular joint:
creation of disc displacement in human autopsy material. J Oral Maxillofac Surg. 1992;50:869-873.
 
16.       Meropol N.J., Hicks DG, Brooks JSJ, Siminovitch KA, Fishman NO, Kant JA, Bennett IS. Coincident Kaposi sarcoma and T -cell lymphoma in a patient with the Wiskott-Aldrich syndrome. Am J Hematol. 1992;40:126-134.
 
17.      Hughes SS, Pellegrini VD, Hicks DG, Goldstein M. Extrapelvic compression of the sciatic nerve: an unusual differential in the diagnosis of pain about the hip. J Bone Joint Surg Am. 1992;74:1553-1559.
 
18.      Kramer K, Hicks DG, Palis J, Rosier RN, Oppenheimer J, Fallon MD, Cohen H. Epithelioid osteosarcoma of bone: immunocytochemical evidence suggesting divergent epithelial and mesenchymal differentiation in a primary osseous neoplasm. Cancer. 1993;71:2977-82.
 
19.      Kreipe RE, Hicks DG, Rosier RN, Puzas IE. Preliminary findings on the effects of sex hormones on bone metabolism in anorexia nervosa. J Adolesc Health. 1993;14:319-324.
 
20.       Adams MJ, Spencer GM, Totterman S, Hicks DGChondromyxoid fibroma.  Skeletal Radiol. 1993;22:150-151.
 
21.       Hicks DG, Krasinskas AM, Sickel JZ, Hughes SS, Puzas JE, Moynes R, Rosier RN. Chondroblastoma: in situ hybridization and immunocytochemical evidence supporting a cartilaginous origin. Int J Surg Pathol. 1994;1(3):155-162.
 
22.       Eisen HJ, Hicks DG, Kant JA, Montone KT, Mull R, Pigott J, Tomaszewski JE.  Diagnosis of post-transplantation lymphoproliferative disorder by endomyocardial biopsy in a cardiac allograft recipient.  J Heart Lung Transplant. 1994;13:241-245.
23.      DiPreta LA, Powers JM, Hicks DG. Hyperostosis cranii ex vacuo: a rare complication of shunting for hydrocephalus. Hum Pathol. 1994;25:545-547.
 
24.      O'Keefe RI, Puzas JE, Loveys LS, Hicks DG, Rosier RN. Analysis of type II and type X collagen synthesis in cultured growth plate chondrocytes by in situ hybridization: Rapid induction of type X collagen in culture. J Bone Miner Res. 1994;9: 1713-1722.
 
25.      Alioto RJ, Naim JO, Hicks DG, Dailey B, DeHaven KE, Lanzafame RI. The healing response of the avascular meniscus using neodynium Y AG laser and fibrin glue: a chromophore assisted technique in a rabbit model. J Clin Laser Med Surg. 1994;12:249-254.
 
26.      Hicks DG, Gokan T, O'Keefe RJ, Totterman SMS, Fultz PJ, Judkins AR, Meyers SP, Rubens DJ, Sickel JZ, Rosier RN. Primary lymphoma of bone: Correlation of magnetic resonance image features with cytokine production by tumor cells. Cancer. 1995;75:973-980.
 
27.      Hughes SS, Hicks DG, O'Keefe RJ, Hurwitz SR, Crabb LQ, Krasinsakas.A, Loveys L, Puzas JE, Rosier RN. Shared phenotypic expression of osteoblasts and chondrocytes in fracture callus. J Bone Miner Res. 1995;10:533-544.
 
28.      Rosier RN, Teot LA, Hicks DG, Schwartz C, O'Keefe RJ, Puzas JE. Multiple drug resistance in osteosarcoma. Iowa Orthop J. 1995;15:66-73.
 
29.      Dalldorf PG, Banas MP, Hicks DG, Pellegrini YD. Rate of degeneration of acetabular cartilage after hemiarthroplasty. J Bone Joint Surg Am. 1995;77:877 -882.
 
30.      Hicks DG, Judkins M, Sickel JZ, Rosier RN, Puzas JE, O'Keefe RJ. Granular histiocytosis of pelvic lymph nodes following total hip arthroplasty: Presence of wear debris, cytokine production, and immunologically activated macrophages. J Bone Joint Surg Am. 1996;78:482-496.
 
31.      Teot LA, O'Keefe RJ, Rosier RN, O'Connell JX, Fox EJ, and Hicks DG. Extraosseous Primary and recurrent giant cell tumors: Transforming growth factor-b1 and b2 expression may explain metaplastic bone formation. Hum Pathol. 1996;27:625-632.
 
32.      Delsignore JL, Ovoretsky PM, Hicks DG, O'Keefe RJ, Rosier RN. Mastocytosis presenting as a skeletal disorder. Iowa Orthop J. 1996;16:126-134.
 
33.      Hicks DG, O'Keefe RJ, Reynolds KJ, Cory-Slechta OA, Puzas JE, Rosier RN. Effects of lead on growth plate chondrocyte phenotype. Toxicol Appl Pharmacol. 1996;140:164-172.
 
34.      O'Keefe RJ, Teot LA, Singh D, Puzas JE, Rosier RN, and Hicks DG. Osteoclasts constitutively express regulators of bone resorption: An immunohistochemical and in situ hybridization study. Lab Invest. 1997;76:457-465.
 
35.      O'Keefe RJ, Loveys LS, Hicks DG, Reynolds PR, Crabb ID, Puzas JE, Rosier RN. Differential regulation of type n and type X collagen synthesis by parathyroid hormone-related peptide in chick growth-plate chondrocytes. J Orthop Res. 1997;15:162-174.
 
36.      Rosier RN, O'Keefe RJ, Teot LA, Fox E, Nestor TA. Reynolds PR, Puzas JE, and Hicks DG. P-glycoprotein expression in cartilage tumors. J Surg Oncol. 1997;65:95-105.
 
37.      Hicks DG, Stroyer BF, Teot LA, O'Keefe RJ. In situ hybridization in skeletal tissues utilizing non-radioactive probes. The J Histotechnol. 1997;20:215-224.
 
38.      Zotalis G, Nayar R, and Hicks DG. Leiomyomatosis peritonealis disseminata, endometriosis and multicystic mesothelioma: an unusual association. Int J Gynecol Pathol.1998;17:178-182.
 
39.      Rappoport AP, Constine LS, Packman CH, Rosier RN, O'Keefe RJ, Hicks DG, Rubin SJ, Rowe JM. Treatment of multifocal lymphoma of bone with intensified PROMACE-CYT ABOM chemotherapy and involved field radiotherapy. Am J Hematol. 1998;58:1-7.
 
40.      Grimsrud CD, Rosier RN, Puzas JE, Reynolds PR, Reynolds SD, Hicks DG, O'Keefe RJ. Bone Morphogenetic Protein-7 in growth plate chondrocytes: regulation by retinoic acid is dependent upon the stage of chondrocyte maturation. J Orthop Res. 1998;16:247-255.
 
41.      O'Keefe RJ, Rosier RN, Teot LA, Stewart JMMM, and Hicks DG. Cytokine and matrix metalloproteinase expression in pigmented villonodular synovitis may mediate bone and cartilage destruction. Iowa Orthop J. 1998;18:26-34.
 
42.      Morishita Y, Rubin SJ, Hicks DG, Kwok E, Seo GS, Totterman SMS. Magnetic resonance imaging of rabbit hip cartilage using a clinical imager and specifically designed surface coils. Acad Radiol. 1998;5:365-373.
 
43.      Ritchlin CT, Haas-Smith SA, Hicks DG, Cappouccio J, Osterland DCK, Looney RJ. Patterns of cytokine production in psoriatic synovium. J Rheumatol. 1998;25:1544-52.
 
44.      Rosier RN, O'Keefe RJ, Hicks DG. The potential role ofTGF-b in fracture healing. Clin Orthop Relat Res. 1998;355 Suppl:S294-S300.
 
45.      Pollice PF, Hsu J, Hicks DG, Bukata S, Rosier RN, Reynolds PR, Puzas JE, O'Keefe RJ. IL-10 inhibits cytokine synthesis in monocytes stimulated by titanium particles: Evidence of an anti-inflammatory regulatory pathway. J Orthop Res. 1998;16:697-704.
 
46.      Larheim TA, Westesson PL, Hicks DG, Eriksson L, Brown D. Osteonecrosis of the temporomandibular joint: Correlation of MRI and histology. J Oral Maxillofac Surg. 1999;57(8):888-98.
 
47.      Doerschuk SH, Hicks DG, Chinchilli VM, Pellegrini VD Jr. Histopathology of the palmar beak ligament in trapeziometacarpal osteoarthritis. J Hand Surg [Am]. 1999;24(3):496-504.
 
48.          Tsingotjidou AS, Zotalis G, Jackson KR, Sawyers C, Puzas JE, Hicks DG, Reiter R, Lieberman JR.  Development of an animal model for prostate cancer cell metastasis to adult human bone.  Anticancer Res. 2001;21:971-978.
 
49.          Rapoport AP, Simons-Evelyn M, Chen T, Sidell R, Luhowskyj S, Rosell K, Obrig T, Hicks DG, Hiknle PM, Nahm M, Insel RA, Abboud CN.  Flavopiridol induces apoptosis and caspase-3 activation of a newly characterized Burkitt’s lymphoma cell line containing mutant p53 genes.  Blood Cells Mol Dis. 2001;27:610-624.
 
50.          Tubbs R, Skacel M, Pettay J, Powell R, Myles J, Hicks D, Sreenan J, Hainfeld J. Interobserver Interpretative Reproducibility of GOLDFISH, A First Generation Gold-Facilitated Autometallographic Bright Field In Situ Hybridization Assay for HER-2/neu Amplification in Invasive Mammary Carcinoma. Am J Surg Pathol. 2002;26:908-913.
51.       Pateder DB, Gish MW, O’Keefe RJ, Hicks DG, Teot LA, Rosier RN. Parathyroid hormone-related peptide expression in cartilaginous tumors.  Clin Orthop Relat Res. 2002;403:198-204.
 
52.       Ritchlin CT, Haas-Smith SA, Ping L, Hicks DG, and Schwarz EM.  Mechanisms of TNF-α and RANKL mediated osteoclastogenesis and bone resorption in sporiatic arthritis. J Clin Invest. 2003;111:821-831.
 
53.       Edmonson JH, Ryan LM, Falkson CI, Hicks DG, Blum RH.  Phase II study of ifosfamide + doxorubicin in patients with advanced synovial sarcoma (E1793): A trial of the Eastern Cooperative Oncology GroupSarcoma. 2003;7:9-11. 
 
54.       Hicks DG, Farver C, Goss G, Goldblum JR.  Harvesting major gains in histopathology and anatomic pathology: The Cleveland Clinic experience. The Bulletin of the Royal College of Pathologists. 2004;128:28-31.
 
55.       Seethala RR, Goldblum JR, Hicks DG, Lehman M, Khurana JS, Pasha TL, Zhang PJ.  Immunohistochemical evaluation of microphthalmia-associated transcription factor expression in giant cell lesions.  Mod Pathol. 2004;17:1491-1496.
 
56.       Hicks DG, Longoria G, Pettay J, Grogan T, Tarr S, Tubbs RR.  In-situ hybridization in the pathology laboratory: general principles, automation, and emerging research applications for tissue based studies of gene expression.  J Mol Histol. 2004;35:595-601.
 
57.       Tubbs RR, Pettay J, Hicks D, Skacel M, Powell R, Grogan T, Hainfeld J.  Novel Bright Field Molecular Morphology Methods for Detection of HER Gene Amplification.  J. Mol Histol. 2004;35:589-594.
 
58.       Yoder BJ, Tso E, Skacel M, Pettay J, Tarr S, Budd T, Tubbs RR, Adams JC, Hicks DGThe expression of fascin, an actin-bundling motility protein, correlates with hormone receptor-negative breast cancer and a more aggressive clinical course.  Clin Cancer Res 2005;11:186-192.
 
59.       Hicks DG, Tubbs RR.  Assessment of the HER2 status in breast cancer by fluorescence in situ hybridization (FISH): A technical review with interpretive guidelines. Hum Pathol. 2005;36:250-261.
 
60.      Lin L, Hicks DG, Xu B, Sigel JE, Bergfeld WF, Montogomery E, Fisher C, Hartke M, Tubbs R, Goldblum JR.  Expression profile and molecular genetic regulation of cyclin D1 expression in epithelioid sarcoma.  Mod Pathol. 2005;18:705-709.
 
61.       Hicks, DG, Yoder BJ, Pettay J, Swain E, Tarr S, Hartke M, Skacel M, Crowe JP, Budd GT and Tubb RR. Incidence of Topoisomerase II-alpha (TOP2A) Genomic Alterations in Adenocarcinoma of the Breast and Their Relationship to HER2 Gene Amplification: A Flourescence In Situ Hybridization Study.  Hum Pathol. 2005;36:348-356.
 
62.          Downs-Kelly E, Yoder BJ, Stoler M, Tubbs RR, Skacel M, Grogan T, Roche P, Hicks, DGThe influence of polysomy 17 on HER2 gene and protein expression in adenocarcinoma of the breast: a fluorescent in-situ hybridization (FISH), immunohistochemical (IHC) and isotopic mRNA in-situ hybridization study.  Am J Surg Pathol. 2005;29:1221-1227.
 
 
63.          Downs-Kelly E, Pettay J, Hicks DG, Skacel M, Yoder BJ, Myles J, Screenan J, Roche P, Powell R, Hainfeld J, Grogan T, Tubbs R.  Analytical validation and interobserver reproducibility of SILVERFISH: A second generation bright field metallography assay for concomitant detection of HER2 gene status and protein expression in invasive carcinoma of the breast.  Am J Surg Pathol. 2005;29:1505-1511.
 
64.          Shao YY, Wang L, Hicks DG, Tarr S, Ballock RT.  Expression and activation of peroxisome proliferator activated receptor in growth plate chondrocytes.  J Orthop Res. 2005;23:1139-1145.
 
65.          Hicks, DG, Dawson, AE, Mattingly S, Crowe JP.  The unmet clinical need for new molecular genetic markers in the prognosis and therapeutic management of breast cancer.  Arch Pathol Lab Med. 2005;129:1372-1374.
 
66.          Tubbs R, Pettay J, Powell R, Hicks DG, Roche P, Powell W, Grogan T, Hainfeld JF.  High-resolution immunophenotyping of subcellular compartments in tissue microarrays by enzyme metallography.  Appl Immunohistochem Mol Morphol. 2005;13:371-375.
 
67.          Haka AS, Volynskaya Z, Gardecki JA, Nazemi J, Lyons J, Hicks D, Fitzmaurice M, Dasari RR, Crowe J, Feld MS. In Vivo margin assessment during partial mastectomy breast surgery using Raman spectroscopy. Cancer Res. 2006;66:3317-3322.
 
68.          Chow WA, Bedell V, Gaytan P, Borden E, Goldblum J, Hicks D, Slovak ML.  Methylthioadenosine phosphorylase gene deletions are frequently detected by fluorescence-in-situ hybridization in conventional chondrosarcomas.  Cancer Genet Cytogenet. 2006;15:95-100.
 
69.          Escobar PF, Patrick RJ, Rybicki LA, Hicks DG, Weng D, Crowe JP.  Prognostic significance of residual breast disease and axillary node involvement for patients who had primary induction chemotherapy for advanced breast cancer.  Ann Surg Oncol. 2006;13:783-787.
 
70.          Ring BZ, Seitz RS, Beck R, Shasteen WJ, Tarr SM, Cheang MCU, Yoder BJ, Budd GT, Nielsen TO, Hicks DG, Estopinal NC, Ross DT.  A novel prognostic immunohistochemical biomarker panel for estrogen receptor-positive breast cancer. J Clin Oncol. 2006;24:3039-3047. 
 
71.          Escobar PF, Patrick RJ, Hicks D, Rim A, Crowe JP.  Multiple myeloma metastatic to the breast.  Breast J. 2006;12:387-388.
 
72.          Hicks DG, Short SM, Prescott NL, Tarr SM, Coleman KA, Yoder BJ, Crowe JP, Choueiri TK, Dawson AE, Budd GT, Tubbs RR, Casey G, Weil R.  Breast cancers with brain metastases are more likely to be estrogen receptor negative, express the basal cytokeratin CK5/6 and over-express HER2 or EGFR.  Am J Surg Pathol. 2006;30:1097-1104.
 
73.          Amend K, Hicks DG, Ambrosone CB.  Breast cancer in African-American women: differences in tumor biology from European-Americans.  Cancer Res. 2006;17:8327-8330.
 
74.          Knott PD, Byrd MC, Hicks DG, Strome M.  Vocal fold healing following laser cordectomy with adjuvant cryotherapy.  Laryngoscope. 2006;116:1580-1584.
 
75.          Shao YY, Wang L, Hicks DG, Ballock RT.  Analysis of gene expression in mineralized skeletal tissues by laser capture microdissection and RT-PCR.  Lab Invest. 2006;86:1089-1095. 
 
76.          Crowe JP, Patrick RJ, Rybicki LA, Escobar PF, Weng D, Budd T, Tubbs RR, Procop GW, Hicks DGA data model to predict HER2 status in breast cancer based on the clinical and pathologic profiles of a large patient population at a single institution.  Breast. 2006;15:728-735.
 
77.          Hicks DG, Yoder BJ, Short S, Tarr S, Prescott N, Crowe JP, Dawson AE, Budd GT, Sizemore S, Muzaffern C, Choueriri T, Tubbs R, Gail D, Nowak N, Accavitti-Loper M, Frost AR, Welch D, Casey G.  Loss of breast cancer metastasis suppressor 1 protein expression predicts reduced disease-free survival in subsets of breast cancer patients.  Clin Cancer Res. 2006;12(22):6702-6708.
 
78.          Tubbs RR, Pettay J, Swain E, Roche PC, Powell W, Hicks DG, Grogan T.  Automation of manual components and image quantification of direct dual label fluorescence in situ hybridization (FISH) for HER2 gene amplification: a feasibility study.  Appl Immunohistochem Mol Morphol. 2006;14(4):436-440. 
 
79.          Crowe JP, Patrick RJ, Rybicki LA, Budd GT, Escobar PF, Tubbs RR, Hicks DG.  HER2 status in bilateral breast cancer.  Int J Fertil Womens Med. 2006;51:219-223.
 
80.       Short SM, Yoder BJ, Tarr SM, Prescott NL, Laniauskas S, Coleman KA, Downs-Kelly E, Pettay JD, Choueiri TK, Crowe JP, Tubbs RR, Budd TG, Hicks DG.  The expression of the cytoskeletal focal adhesion protein paxillin in breast cancer correlates with HER2 overexpression and may help predict response to chemotherapy: A retrospective immunohistochemical study.  Breast J. 2007;13:130-139.
 
81.       Ghadersohi A, Pan D, Fayazi Z, Hicks DG, Winston JS, Li F.  Prostate-derived Ets transcription factor (PDEF) down regulates survivin expression and inhibits breast cancer cell growth in vitro and xenograft tumor formation in vivo.  Breast Cancer Res Treat. 2007;102:19-30.
 
82.       Powell WC, Hicks DG, Prescott N, Tarr SM, Laniauskas S, Williams T, Short S, Pettay J, Nagel RN, Dabbs DJ, Scott KM, Brown RW, Grogan T, Roche PC, Tubbs R.  A new rabbit monoclonal antibody (4B5) for the immunohistochemical (IHC) determination of the HER2 statusin breast cancer: comparison with CB11, fluorescence in situ hybridization (FISH) and interlaboratory reproducibility.  Appl Immunohistochem Mol Morphol. 2007;15:94-102.
 
83.       Tubbs RR, Swain E, Pettay JD, Hicks DG.  An approach to the validation of novel molecular markers of breast cancer via TMA-based FISH scanning.  J Mol Histol. 2007;38:141-150.
 
84.      Sossey-Alaoui K, Safina A, Li X, Vaughan MM, Hicks DG, Bakin AV, Cowell JK.  Down-regulation of WAVE3, a metastasis promoter gene, inhibits invasion and metastasis of breast cancer cells.  Am J Pathol. 2007;170:2112-2121.
 
85.       Goldstein NS, Hewitt SM, Taylor CR, Yaziji H, Hicks DGRecommendations for improved standarization of immunohistochemistry.  Appl Immunohistochem Mol Morphol. 2007;15:124-133.
 
86.       Leitman SA, Prescott NL, Hicks DG, Westra WK, Levine MA.  SH3BP2 is rarely mutated in exon 9 in giant cell lesion outside cherubism. Clin Orthop Relat Res. 2007;459:22-27.
 
87.       Head K, Gong S, Joseph S, Wang C, Burkardt T, Rossi MR, LaDuca J, Matsui S-I, Vaughn M, Hicks DG, Heinz N, Cowell JK.  Defining the expression pattern of the LGI1 gene in BAC transgenic mice.  Mamm Genome. 2007;18:328-337.
 
88.  Lo KC, Rossi MR, LaDucca J, Hicks DG, Turpaz Y, Hawthorn L, Cowell JK.  Candidate
glioblastoma development gene identification using concordance between copy number abnormalities as defined by array comparative genomic hybridization and gene exp, , , ression levels.  Genes Chromosomes Cancer. 2007;46:875-894.
 
89.       Nowak NJ, Miecznikowski J, Moore SR, Gaile D, Bobadilla D, Smith DD, Kernstine K, Forman SJ, Mwahech-Fauceglia P, Reid M, Stoler D, Loree T, Rigual N, Sullivan M, Weiss LM, Hicks D, Slovak ML.  Challenges in array CGH for the analysis of cancer samples.  Genet Med. 2007;9:585-595.
 
90.       Tubbs RR, Hicks DG, Cook J, Downs-Kelly E, Pettay J, Hartke MB, Hood l, Neelon R, Myles J, Budd GT, Moore HC, Andresen S, Crowe J.  Fluorescence In Situ Hybridization (FISH) as primary methodology for the assessment of HER2 status in adenocarcinoma of the breast: a single institution experience.  Diagn Mol Pathol. 2007;16:207-210.
 
91.       Hicks DG, Kulkarni S.  HER2-positive breast cancer: review of biologic relevance and optimal use of diagnostic tools.  Am J Clin Pathol. 2008;129:263-273.
 
92.       Kapural L, Mekhail N, Hicks D, Kapural M, Sloan S, Moghal N, Ross J, Petrinec D.  Histological changes and temperature distribution studies of a novel bipolar radiofrequency heating system in degenerated and non-degenerated human cadaver lumbar discs.  Pain Med. 2008;9:68-75.
 
93.       Smith R, Hicks D, Tomljanovich PI, Lele SB, RajputA, Dunn KB.  Adenocarcinoma arising from chronic perianal Crohn’s disease: case report and review of the literature.  Am Surg. 2008;74:59-61.
 
94.       Kulkarni S, Hicks DG.  HER2-positive early breast cancer and trastuzumab: a surgeon’s perspective.  Ann Surg Oncol. 2008;15:1677-1688.
 
95.       Meguerditchian AN, Malik D, Hicks DG, Kulkarni S.  Solitary fibrous tumor of the breast and mammary myofibroblastoma: the same lesion?  Breast J. 2008;14:287-292.
 
96.       Hicks DG, Kulkarni S.  Trastuzumab as adjuvant therapy for early breast cancer: The importance of accurate HER2 testing.  Arch Pathol Lab Med. 2008;132:1008-1015.
 
97.       Vaidya KS, Harihar S, Phadke PA, Stafford LJ, Hurst DR, Hicks DG, Casey G, DeWald DB, Welch DR.  Breast cancer metastasis suppressor-1 differentially modulates growth factor signaling.  J Biol Chem. 2008;283:28354-60. Jul 29, 2008 [epub]
 
98.       Hicks DG, Hammond E, Kulkarni S.  The role of the indispensable pathologist in the diagnosis and treatment planning for breast cancer.  Arch Pathol Lab Med. 2008;132(8):1226-1227.
 
99.       Wei B, Wang J, Bourne P, Yang Q, Hicks D, Bu H, Tang P. Bone metastasis is strongly associated with ER positive/PR negative breast carcinomas.  Hum Pathol 2008;39:1809-15. 2008 Aug 18. [Epub]
 
100.     Zhang Y, Sieuwerts AM, McGreevy M, Casey G, Cufer T, Paradiso A, Harbeck N, Span PN, Hicks DG, Crowe J, Tubbs RR, Budd GT, Lyons J, Sweep CGJ, Schmitt M,        Schittulli F, Golouh R, Talantov D, Wang Y, Foekens JA.  76-gene signature to predict benefit of tamoxifen in node-negative, estrogen receptor-positive breast cancer patients.  Breast Cancer Res Treat 2008 Sep 23. [Epub ahead of print]
 
101.     Yaziji H, Taylor CR, Goldstein N, Dabbs D, Hammond E, Hewlett B, Floyd A, Barry A, Martin A, Badve S, Baehner F, Cartun R, Eisen R, Swanson P, Hewitt S, Vyberg M, Hicks DG.  Consensus recommendations on estrogen receptor testing in breast cancer      by immunohistochemistry.  Appl Immunohistochem Mol Morphol 2008;16:513-520. 2008 Oct 16 [Epub ahead of print].
 
102.       Chen SC, Henry DO, Hicks DG, Reczek PR, Wong MK.  Intravesical administration of    plasminogen activator inhibitor type-1 inhibits in vivo bladder tumor invasion and    progression.  J Urol 2008 Nov 14 [Epub ahead of print]
 
 
Editorials and Letters to the Editor:
 
103.    Hicks DGPharmacogenomics, HER-2/neu, and New Application for Diagnostic Pathology.  Advance for Administrators of the Laboratory, July, 2003, pp.17.
 
104.     Tubbs R, Hsi ED, Hicks DG, Goldblum JR.  Molecular Pathology Testing of Tissues Fixed in Pefer Solution.  Am J Surg Pathol 2004; 28:417-419.
 
105.     Tubbs, RR, Hicks DGHER-2 Testing in Breast Cancer.  JAMA. 292:1817-1818; 2004.
 
106.     Kulkarni S, Hicks DG. Surgical decision-making and the influence of biologic markers: Reply.  Ann Surg Oncol 2008 Sept 23 (epub ahead of print).
 
Manuscripts in press:
 
107.     Fang X, Hicks DG, Zhang S.  Osteoclast-like giant cell tumor of the salivary gland.  Ann Diagn Pathol.  In Press.
 
108.       Chuang C, Hicks DG, Berenson M, Kulkarni S, Tang P.  Benign epithelial inclusion of       axillary lymph nodes: Report of two cases.  Breast J.  In Press.
 
109.       Tang P, Wei B, Hicks DG, Skinner K, Bu H.  Molecular classifications of breast   carcinoma by IHC analysis, are they ready for clinical use? Diag Mol Pathol.  In Press
 
 
Submitted or in preparation:
 
Bhatti Z, Dennis CG, Feminella J, Bushey J, Shirkant PA, Hicks DG, Brun YF, Almyroudis NG, Lewis R, Romani L, Holland SM, Petraitiene R, Walsh TJ, Segal BH.  Host defense against aspergillosis in the p47phox-/- mouse model of chronic granulomatous disease. Journal of Immunology (Submitted)
 
 
 
Khoury T, Mojica W, Hicks DG, Janarthanan B, Tan J, Tian C, Edge S, Cheney RT.  HER2 juxtamembrane domain (trastuzumab binding site) gene mutations in invasive breast cancers over-expressing the HER2 gene: a potential modifier of trastuzumab response and HER2 protein function. The Breast Journal. Submitted
 
Chen F, Hicks DG. Kim H, Bundy BN, Sait S, Zhang S.  Renal epithelioid agiomyolipoma expresses higher level of EGFR than its conventional type.  Appl Immunohistochem Mol Morphol.  Submitted
 
Kulkarni S, Hicks DG, Watroba N, Murekeyisoni C, Hwang H, Khoury T, Beck RA, Ring BZ, Estopinal N, Schreeder M, Seitz RS, Ross DT.  TLE3 as a candidate biomarker of response from cell cycle stage specific chemotherapy in breast cancer.  Clinical Cancer Research, Submitted
 
Dim DC, Starostik P, Iwenofu H, Hicks DG, Cheney R, Merzianu M.  Clonal monocytoid B-cell proliferation associated with adenocarcinoma of the lungIn Preparation
 
Angitapalli R, Hicks DG, Janarthanan B.  Pneumocystis carinni pneumonia in a patient receiving adjuvant chemotherapy for breast cancerIn Preparation
 
Dim DC, Ravi V, Henry D, Hicks DG, Wong MK.  The expression of the actin-bundling motility protein fascin and vascular endothelial growth factor (VEGF) in human angiosarcoma.  In Preparation 
 
Hicks DG, Barron J, Cziraky M, Weisman T.  HER2 testing and subsequent trastuzumab treatment for breast cancer in a managed care environmentIn Preparation
 
Sizemore S, Hicks DG, Aung PP, Prescott N, Short S, Tarr S, Budd GT, Tubbs R, Crowe J, and Casey G.  Podocalyxin is associated with a basal-like breast cancer phenotype and increased metastasis to the brainIn Preparation
 
Reviews:
 
1.    Hicks DG, Connor AM, Laposata M. Laboratory diagnosis and monitoring of
disseminated intravascular coagulation. Lab Med 18(9):585-589; 1987.
 
2.    Hicks DG, Connor AM, Laposata M. Laboratory diagnosis and monitoring of disseminated
intravascular coagulation. Reprinted in Biochemica Clinica 13:30-34, 1989. (originally printed in Lab Med, 18(9):585-589, 1987.)
 
3.         Hicks DG, LiVolsi VA. Malignant lymphoma simulating hairy cell leukemia (Neiman's Disease).American Society of Clinical Pathologists (ASCP) Check Sample, Anatomic Pathology II, No. APII 88-9 (AP11-141).
 
4.         Hicks DG, Tubbs RR.  HER2 Status in Breast Cancer: Implications for Prognosis and Therapy.  Biological Therapy of Breast Cancer.  5:3-6;2004.
 
Chapters:
 
1.         Rowley PT, Ohlsson-Wilhelm BM, Hicks DG, Rudolph NS, Farley B, Kosciolek B, LaBella S.Regulation of hemoglobin synthesis in K-562 human erythroleukemia cells. In: Regulation of Hemoglobin Biosynthesis. Shupe JL, Peterson HB, Leone NC (eds.), Paragon Press, Inc., Salt Lake City, UT, 1983.
2.         Puzas JE, Hicks DG, Reynolds SO, O'Keefe RJ. Regulation of osteoclastic activity in infection. In:Methods in Enzymology. Bacterial Pathogenesis, Part B; Interaction of pathogenic bacteria with host cells. Vol 236: p 47-56, Academic Press, San Diego, New York, 1994.
 
3.            Kant J, Hicks DG. The interpretation of nonlymphoid elements in lymph node biopsy specimens.In: Surgical Pathology of the Lymph Nodes and Related Organs. second edition. Jaffe ES (ed.), p. 594-623, W.B. Saunders Company, Philadelphia, 1994.
 
4.            Rosier RN, Hicks DG. Sarcomatous bone formation. In: Bone Formation and Repair. Brighton CT, Friedlanender GE, Lane 1M (eds.), p 93-107; American Academy of Orthopaedic Surgeons, Rosemont... IL, 1994.
 
5.    Rosier RN, Hicks DG, Teot LA, Puzas JE, O'Keefe RJ. Mechanisms of Bone Metastasis.
Assessment and Treatment of Cancer Pain, Progress in Pain Research and Management, Vol. 12, edited by R. Payne, R. Patt, and C.S. Hill, IASP Press, Seattle, (ã1998).
 
6.         Skacel M, Hicks DG, Tubbs RR.  Chapter 2.3:  Tissue Microarrays and their Modifications in High-Throughput Analysis of Clinical Specimens.  In Immunohistochemistry and In Situ Hybridization of Human Carcinomas; Molecular Genetics; Lung and Breast Carcinomas.  M. A. Hayat, (ed), Humana Press, USA.  pp57-65;2004.
 
7.         Nitta H, Hicks D, Skacel M., Pettay J, Grogan T., and Tubbs RR. Molecular Morphology of Human Tissues. High-Throughput Morphologic Gene Expression Studies Using Automated mRNA In Situ Hybridization Amplifications and Tissue Microarrays for past-genomic and clinical research.  Series Editors: Jiang Gu & Gerhard Hacker . Book Series Editors Vol II: G Hacker & R Tubbs.  CRC Press. pp. 147-156;2005
 
8.         Tubbs RR, Pettay J., Skacel M, Powell R, Hicks D, and Hainfeld J. Molecular Morphology of Human Tissues. GOLD and SILVER-Facilitated Metallographinc In Situ Hybridization Procedures for Detection of HER2 Gene Amplification. Series Editors: Jiang Gu & Gerhard Hacker . Book Series Editors Vol II: G Hacker & R Tubbs.  CRC Press. pp. 101-106;2005.
 
9.        Hicks DG.  Metastatic Disease to the Musculoskeletal System.  Cancer in the Spine:  Handbook of Comprehensive Care.  Editor: Robert F. McLain.  Humanna Press.  Pp. 7-16;2006
 
10.       Hicks DG. Molecular Pathology of Breast Cancer.  Cell and Tissue Based Molecular Pathology.  Series Editors: Tubbs R, and Stoler M.  Saunders. Pp. 358-376;2008.
 
Book reviews:
 
1.         Hicks DG. Review of: Bone and Soft Tissue Tumors. by M. Campanacci, F. Bertoni, and P.Bacchini. New York: Springer-Verlag Wein, 1990. Am J Surg Pathol, 16:311-312, 1992.
 
2.         Hicks DG.  Review of: AFIP Atlas of Tumor Pathology Series 4 – Tumor of the Bones and Joints.  Am J Surg Pathol. 31:158;2007
 
Texts:
 
Laposata M, Connor AM, Hicks DG, Phillips D. Manual of Clinical Hemostasis. Yearbook Medical Publishers, 1989.
 
Published abstracts presented at national meetings:
 
Hicks DG, Ohlsson-Wilhelm BM, Farley BA, Kosciolek BA, Rowley PT. K-565 human leukemia
cell erythroid induction requires a factor found in fetal bovine serum resembling a tryptic
fragment of transferrins. In: Blood Supplement. November 1982. Presented at Symposium of Medical Student Research. University of Rochester School of Medicine and Dentistry, January 15, 1981; and. Residents' Day Grand Rounds, Department of Pathology, University of Rochester Medical Center, June 2. 1982.
 
Hicks DG. LiVolsi VA. Neidich JA. Puck JM, Kant JA. Solitary follicular nodules of the thyroid
are clonal proliferations. Lab Invest 60:40A, 1989. (Poster presentation. 1989 United States
and Canadian Academy of Pathology Meeting. San Francisco, CA. Winner of Stowell-Orbison Award).
 
Hicks DG, Tomaszewski J. Connor AM. Roberts S, Prystowsky M, Kant JA. Monoclonal
antibodies to irnrnunophenotype non-Hodgkin's lymphomas in Bouin's fixed tissue: Correlation with gene rearrangement studies. Lab Invest 60:40A. 1989. (Poster presentation. 1989 United States and Canadian Academy of Pathology Meeting, San Francisco, CA).
 
Louie DC. Hicks DG, Hellman FN. Brooks JSJ, Prystowsky MB, Kant JA: B-cell predominance in
recurrent Hodgkin's disease: Multiparameter studies. Lab Invest 62:60A. 1990. (Poster
presentation, 1990 United States and Canadian Academy of Pathology Meeting, Boston. MA).
 
Hicks, DG, Sack MJ, Laposata EA, Kant JA, Brooks JSJ. Primary cardiac lymphoma: An
immunophenotypic and genotypic analysis of 2 cases. Lab Invest 62:44A.1990 (Poster
presentation, 1990 United States and Canadian Academy of Pathology Meeting, Boston. MA).
 
Hicks DG, August T, Roberts SA. LiVolsi VA. Expression of "lymphocyte homing receptor"
(CD44) in the thyroid. Lab Invest 62:44A, 1990. (Poster presentation. 1990 United States and Canadian Academy of Pathology Meeting, Boston, MA).
 
Soslow R, Hicks DG, Berger M, Gaines L, Cassileth P, Prystowsky M. Kant J. Clinicopathologic
heterogeneity in diffuse mixed lymphoma. Mod Pathol 4:494A.199 I. (Poster presentation,
1991 United States and Canadian Academy of Pathology Meeting).
 
Hughes S, Hicks DG, Rosier R. Transforming growth factor beta causes a hyperplastic synovial
response in rat knees. Orthopaedic Transactions. 1 Bone Joint Surg 15:627-628A.1991.
(Presented by Dr. Hughes at the twenty-fourth Annual Residents' Conference, April 1991,
Kansas City).
 
Myers MA, Hicks DG, Looney RJ, Frick KK, Rosier RN, Furlanetto RJ, Puzas JE. MG63
osteosarcoma cells express features of an osteoclastic phenotype. J Bone Miner Res
6:(supplement 1);262A,1991. (poster presentation, 1991 American Society for Bone and
Mineral Research Meeting, San Diego, CA).
 
Sawyer JR, Hicks DG, Cosgarea A, Puzas lE, Rosier RN. In situ hybridization and
immunohistochemical characterization of a rare cartilage tumor before and after chemotherapy.  Transactions of the 38th annual meeting of the Orthopaedic Research Society, 17:445A.1992.  (Poster presentation, 1992 Orthopaedic Research Society Annual Meeting, Washington. D.C.).
Willis J, Hicks DG, Sickel JZ, deMesy Jensen KL, Rosier RN, Hoxen A, Dawson, AE.
Proliferating cell nuclear antigen (PCNA) expression in malignant fibrous histiocytoma: an
immunocytochemical analysis of 18 cases. Lab Invest 66:58A, 1992. (Poster presentation, 1992 United States and Canadian Academy of Pathology Meeting, Atlanta. GA).
 
Loveys L, Crabb I, O'Keefe R, Reynolds P, Hicks DG, Puzas JE, Rosier R. Differential pre-
translational regulation of type II and type X collagen synthesis by parathyroid hormone and parathyroid hormone related peptide in chick growth plate chondrocytes. J Bone Miner Res 7:(supplement 1);557A.1992. (Poster presentation, 14th annual meeting of the American Society for Bone and Mineral Res, 1992).
 
Rosier RN, Burton RI, Hicks DG, Puzas JE. Multiple drug resistance gene expression in bone
sarcomas. (Platform presentation by Dr. Rosier, American Orthopaedic Association Meeting Toronto, Ontario, Canada, 1992).
 
Naduri P, Hicks DG, Davis N, Rosier RN, Puzas JE. Reynolds PR. Characterization of ubiquitin
expression in cartilaginous tumors: correlation of immunohistochemical staining with tumor
grade. Mod Pathol 6:3IA, 1993. (Poster presentation, 1993 United States and Canadian
Academy of Pathology Meeting, New Orleans, LA).
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Mongeon C, Sickel J, Hicks DG, Freund G, Nanduri P, Reynolds PR. Immunohistochemical
analysis of ubiquitin expression in hematopoietic tissues and lymphoid cell lines. Mod Pathol 6:556A, 1993. (Poster presentation, 1993 United States and Ca, n, adian Academy of Pathology Meeting, New Orleans, LA).
 
Sheils LA, Hicks DG, Ryan DH. Discrepancies between bone marrow biopsies and aspirate
smears: A study of96 consecutive cases. Mod Pathol 6:578A,1993. (Poster presentation, 1993 United States and Canadian Academy of Pathology Meeting, New Orleans, LA).
 
Brooks JSJ, Elenitsas R, Hicks D, Elder D. Proliferative cutaneous angiomatosis: A cellular tumor
mimicking angiosarcoma and Kaposi's sarcoma. Mod Pathol 6:6A,1993. (Platform
presentation by Dr. Brooks, 1993 United States and Canadian Academy of Pathology Meeting, New Orleans, LA).
 
Doerschuk SH, Hicks DG, Reynolds PR, Pellegrini YD. The histopathology of the
trapeziometacarpal joint and its volar "beak" ligament. Orthopaedic Transactions, J Bone Joint Surg 17:147A,1993; (Presented at the Eastern Orthopaedic Association annual meeting by Dr. Doerschuk).
 
Puzas JE, Ishibe M, Parker IF, de Mesy Jensen KL, Hicks DG, Rosier RN. A hypothesis to
explain the spatial coupling of bone formation to bone resorption. Transactions of the 39th
annual meeting of the Orthopaedic Research Society, 18:18A,1993. (Platform presentation by Dr. Puzas, 1993 Orthopaedic Research Society Annual Meeting, San Francisco, CA).
 
Rosier RN, Loveys LS, Crabb ID, O'Keefe RJ, Reynolds PR, Hicks DG, Puzas JE. Digital image
analysis of in situ hybridization data demonstrates pre-translational regulation of type X collagen synthesis by parathyroid hormone related peptide in growth plate chondrocytes. Transactions of the 39th annual meeting of the Orthopaedic Research Society, 18:667A,1993. (Poster presentation, 1993 Orthopaedic Research Society Annual Meeting, San Francisco, CA).
 
 
 
Schwartz CL, Hicks DG, Weiner M, Rosier RN. The use of CSA to overcome drug resistance.
Proceedings of the American Society of Clinical Oncology, 12:1427A,1993. (Presented by Dr. Schwartz at the 29th Annual Meeting, Orlando, FL, 1993).
 
Rosier RN, Hicks DG, Puzas JE, O'Keefe RJ, Hoyen AH. Multidrug resistance gene expression in
Ewing's sarcoma. (Platform presentation by Dr. Rosier, 1993 American Orthopaedic Association Meeting, San Diego, CA).
 
Doerschuk SH, Hicks DG, Pellegrini YD. The histopathology of the volar beak ligament in basal
joint osteoarthritis. (Presented by Dr. Doerschuk. 1993 American Society for Surgery of the
Hand. Annual Meeting).
 
Hicks DG. deMesy Jensen KL. Parker JF, Rosier RN. Puzas JE. Immunohistochemical analysis of
lysosomal enzyme activity during abnormal bone remodeling. J Bone Miner Res 8:(supplement 1); 1101A.1993. (Poster presentation. 15th annual meeting of the American Society of Bone and Mineral Research. 1993. Tampa. FL).
 
Reynolds PR. Rosier RN. Hicks DG. Puzas JE. Involvement of ubiquitin in osteoclast activity. Journal of Bone and Mineral Research. 8:(supplement 1);1102A. 1993. (Poster presentation. 15th annual meeting of the American Society of Bone and Mineral Research. 1993, Tampa, FL).
 
Hatem F, Hicks DG, Dawson AE. Immunohistochemical analysis of p53 and PCNA expression in
uterine papillary serous carcinoma: Comparison to classic endometrial adenocarcinoma. Am J Clin Pathol 100:54A.1993. (Poster presentation. 1993 Fall Meeting of the American Society of Clinical Pathologists, Orlando, FL).
 
Sebastianelli WJ, Gillespie MJ, DeHaven KE, Hicks DG, Cosgarea AJ. The histopathology of
arthrofibrosis following ACL reconstruction. Orthopaedic Transactions, J Bone Joint Surg,
17: 1227A. 1993. (Presented by Dr. Sebastianelli at the 1993 American Academy of Orthopaedic Surgeons Scientific Program. San Francisco, CA).
 
Sebastianelli WJ, Brooks DH, Hicks DG, DeHaven KE. An analysis of the effects of suture technique on the vascular supply of the medial meniscus. Orthopaedic Transactions, J Bone Joint Surg 17: 1228A.1993. (Presented by Dr. Sebastianelli at the 1993 American Academy of Orthopaedic Surgeons Scientific Program. SanFrancisco, CA).
 
Rosier RN, Hicks DG, Fox E, Nestor T, O'Keefe RJ, deMesy Jensen KL. Reynolds PR, Puzas JE.
Constitutive expression of P-glycoprotein in chondrosarcoma may explain chemotherapeutic resistance. Trans Orthop Res Soc 19:252A,1994. (Platform presentation by Dr. Rosier, 1994 Orthopaedic Research Society Annual Meeting, New Orleans. LA).
Rosier RN. Schnell J, Hicks DG. Reynolds PR. Hoxen AT, deMesy Jensen KL. O'Keefe RJ,
Puzas JE. Expression of NM23 in soft tissue sarcomas. Trans Orthop Res Soc 19:764A.
1994. (Poster presentation. 1994 Orthopaedic Research Society Annual Meeting, New Orleans. LA).
deMesy Jensen KL. Hicks DG. Reynolds PR. Puzas IE, ScrewIer GJ, Nissenson RA, Hurwitz SA,
Rosier RN. Immunolocalization of PTHrP in chicken and human growth plate and articular
cartilage. Trans Orthop Res Soc 19:417A,1994. (Poster presentation, 1994 Orthopaedic
Research Society Annual Meeting. New Orleans, LA).
 
 
 
 
Puzas JE, Dipreta J, Jocuns-Wilson J, Hicks DG, Rosier RN. Growth factor content of bone may
not be a predictor of skeletal density at all sites in the body. Trans Orthop Res Soc 19: 130A, 1994. (Platform presentation by Dr. Puzas, 1994 Orthopaedic Research Society Annual Meeting, New Orleans, LA).
 
O'Keefe RJ, Hicks DG, Reynolds PR. Puzas JE, Rosier RN. C-fos expression and chick growth
plate chondrocyte differentiation. Trans Orthop Res Soc 19: 168A.1994. (Platform presentation by Dr. O'Keefe. 1994 Orthopaedic Research Society Annual Meeting. New Orleans, LA).
 
Reynolds PR, Nanduri P, Rosier RN, Puzas JE, Hicks DG. Involvement of ubiquitin in normal and
pathological changes in skeletal tissue. Trans Orthop Res Soc 19:424A, 1994. (Poster
presentation, 1994 Orthopaedic Research Society Annual Meeting, New Orleans, LA).
 
Dawson AE, Hatem F, Hicks DG, Moynes R, Angel C. Multidrug resistance in uterine papillary serous carcinoma (UPS): comparison with classic endometrial adenocarcinoma. Mod Pathol 7:87 A, 1994. (Poster presentation, 1994 United States and Canadian Academy of Pathology Meeting, San Francisco, CA).
 
Hicks DG, O'Keefe RJ, Judkins A, Cory-Slechta DA, Puzas JE, Stroyer BF, Rosier RN. In vitro
and in vivo effects of lead on skeletal tissues. J Bone Miner Res 9:(supplement 1);A154, 1994. (Poster presentation, 16th annual meeting of the American Society of Bone and Mineral Research, 1994, Kansas City, MO).
 
Sebastianelli WJ, Schnell J, Gillespie MJ, DeHaven KE, Hicks DG. Detennination of TGFB levels
in synovial fluid in patients with arthrofibrosis. Orthopaedic Transactions, J Bone Joint Surg, 19:500A, 1995. (Presented by Dr. Sebastianelli at the 1995 American Academy of Orthopaedic Surgeons Scientific Program, Orlando, FL).
 
Willis J, Hicks DG, Teot LA, Rosier RN, Abdul-Karim FW, Puzas JE. Immunocytochemical
localization of lysosomal enzymes in skeletal disorders with abnormal bone remodeling. Mod Pathol,8:59A,1995. (Poster presentation, .1995 United States and Canadian Academy of Pathology Meeting, Toronto, ONT, Canada).
 
Singh D, Hicks DG, Rosier RN, Puzas JE, Stroyer BF, O'Keefe RJ. Autocrine / paracrine
expression of cytokines by osteoclasts in physiologic and pathologic states. Mod Pathol 8:46A, 1995. (Poster presentation, 1995 United States and Canadian Academy of Pathology Meeting, Toronto, ONT, Canada).
 
Judkins AR, Sickel JZ, Hicks DG, Suster SS, Rosier RN, Puzas JE, Moynes R, O'Keefe RJ.
Granular histiocytosis of pelvic lymph nodes following total hip arthroplasty. Mod Pathol
8:20A, 1995. (Poster: Presentation, 1995 United States and Canadian Academy of Pathology Meeting, Toronto, ONT, Canada).
 
Hicks DG, Reynolds K, O'Keefe RJ, Judkins A, Cory-Slechta DA, Puzas JE, Rosier RN. The
effects of lead on skeletal development. Mod Pathol 8:809A,1995. (Poster presentation, 1995 United States and Canadian Academy of Pathology Meeting, Toronto, ONT, Canada).
 
Hicks DG, Reynolds K, O'Keefe RJ, Puzas JE, Rosier RN. Effects of lead on autocrine/paracrine
regulation of growth plate chondrocytes. J Bone Miner Res 10:(supplement 1);T274A,1995.
(Poster presentation, 17th annual meeting of the American Society for Bone and Mineral
Research, 1995, Baltimore, MD).
O'Keefe RJ, Teot LA, Singh D, Rosier RN, Puzas JE, Hicks DG. Expression of resorption
stimulating cytokines by osteoclasts: Evidence for autocrine/paracrine regulation. J Bone Min Res 10:(supplement 1);M332A, 1995. (Poster presentation, 17th annual meeting of the American Society for Bone and Mineral Research, 1995, Baltimore, MD).
 
Teot LA, Hicks DG, O'Keefe RJ, Rosier RN. Cytokine expression in Ewing's sarcoma /
primitive neuroectodermal tumor: A possible mechanism mediating osteoclastic activity and
bone destruction. (Platform presentation by Dr. Teot, 1995 Society for Pediatric Pathology
Interim Meeting, Baltimore, MD).
 
Martinez DA, Hicks DG, Rosier RN, O'Keefe RJ, Stroyer BF, Puzas JE. Localization of
lysosomal enzymes and complex carbohydrates in osteoclastic resorption lacunae in an ill
vitro remodeling system. Trans Orthop Res Soc 2 I : 107 A,1996. (Platform
presentation by Dr. Martinez, 1996 Orthopaedic Research Society Annual Meeting,
Atlanta, GA).
 
Teot LA, Hicks DG, O'Keefe RJ, Puzas JE, Rosier RN. Matrix metalloproteinase and cytokine expression in Ewing's sarcoma / primitive neuroectodermal tumor: A possible mechanism mediating bone destruction. Trans Orthop Res Soc 21: l82A,1996. (Platform presentation by Dr. Teot, 1996 Orthopaedic Research Society Annual Meeting, Atlanta, GA).
 
Pearson WG, Batley J, O'Keefe RJ, Puzas JE, Reynolds PR, Hicks DG, Rosier RN.
Suppression of metastatic potential by inhibition of matrix metalloproteinase. Trans
Orthop Res Soc 21: l84A,1996. (Platform presentation by Dr. Rosier, 1996
Orthopaedic Research Society Annual Meeting, Atlanta, GA).
 
Hicks DG, Martinez DA, Zuscik MJ, Rosier RN, Stroyer BF, Puzas JE. The effects of lead on
osteoclastic function and bone turnover: An experimental model. Mod Pathol 9: 146A,1996.
(Poster presentation, 1996 United States and Canadian Academy of Pathology Meeting,
Washington, D.C.).
 
Chouairy C, Teot LA, Rosier RN, O'Keefe RJ, Hicks DG. Cytokine expression in Langerhans cell
histiocytosis: an immunohistochemical study. Mod Pathol 9:5A, 1996. (Poster presentation,
1996 United States and Canadian Academy of Pathology Meeting, Washington, D.C.).
 
Stewart JMM, Teot LA, O'Keefe RJ, Rosier RN, Hicks DG. Localization of cytokines and matrix
metalloproteinase production in pigmented villonodular synovitis. Mod Pathol 9: 14A,1996. (Poster presentation, 1996 United States and Canadian Academy of Pathology Meeting, Washington, D.C.).
 
Saunders C, Teot LA, DelSignore JL, Rosier RN, Dvoretsky PM, Hicks DG. Mast cell disease
presenting as a solitary skeletal lesion: a report of three cases. Mod Pathol 9:l3A,1996. (Poster presentation, 1996 United States and Canadian Academy of Pathology Meeting, Washington, D.C.).
 
Katzman P, Hicks DG, Geisinger KR, Rosier RN, Teot LA. Immunohistochemical detection of P-
glycoprotein in rhabdomyosarcoma: correlation with patient outcome. Mod Patho19:8A,1996 (Poster presentation, 1996 United States and Canadian Academy of Pathology Meeting, Washington, D.C.).
 
 
 
 
Hicks DG, Rosier RN, Constine L, Gregoritch S, O'Keefe RJ. Radiation effect on growth factor
expression and chondrocyte regulation in the epiphyseal growth plate. Int J Radiat Oncol Biol Phys 37(suppl): 167,1996. (Platform presentation, 1996 ASTRO meeting, Los Angles, CA).
 
McCance S, Constine LS, Hicks DG, O'Keefe RJ, Watelet LM, Maseelall P, Puzas IE, Rosier RN.
Effects of radiation treatment on bone mass. J Bone Min Res ll:(supplement 1);S54lA,1996.
(Poster presentation, 18th annual meeting of the American Society for Bone and Mineral
Research, 1996, Seattle, WA).
 
O'Keefe RJ, Hicks DG, Pollice P, Teot LA, Puzas JE, Rosier RN. Cytokine and growth factor
expression in carcinomas with skeletal metastasis. J Bone Min Res 11:(supplement
1 );S360A, 1996. (Poster presentation, 18th annual meeting of the American Society for Bone and Mineral Research, 1996, Seattle, WA).
 
Puzas JE, Hicks DG, O'Keefe RI, Martinez DA, Zuscik MI, Fullmer C, Rosier RN. Effects of lead
on skeletal remodeling. J Bone Min Res 11 :(supplement 1 );S537 A, I 996. (Poster presentation 18th annual meeting of the American Society for Bone and Mineral Research, 1996, Seattle, WA).
 
Martinez DA, Hicks DG, Rosier RN, O'Keefe RI, Reynolds PR, Stroyer BF, Sarin H, Puzas JE.
In vitro bone remodeling: Potential mechanisms for site directed bone formation. J Bone Min Res 11 :(supplement 1 ); M371 A, 1996. (Poster presentation, 18th annual meeting of the American Society for Bone and Mineral Research, 1996, Seattle, WA).
 
Teot LA, Kilpatrick SE, Hicks DG, O'Keefe RJ. Myositis ossificans: Variations in fine needle
aspiration biopsy cytology correlate with lesional maturation. Acta Cytol 40: 1089,1996. (Poster presentation, 44th Annual Scientific Meeting of the American Society of Cytology, 1996, Denver, CO).
 
VerNooy RA, Hicks DG, O'Keefe RJ, Grimsrud C, Teot LA. Heterotopic ossification in sigmoid
colon carcinoma: Expression of osteoinductive factors by tumor cells may explain stromal bone formation. Lab Invest 76: 154A,1997. (Poster presentation,1997 United States and Canadian Academy of Pathology Meeting, Orlando, FL).
 
Rosier RN, O'Keefe RJ, Gunter KK, D'Souza M, Puzas JE, Hicks DG, Reynolds PR, and Gunter
TE. PTHrP modulates volume regulatory mechanisms which control chondrocyte maturation. J Bone Min Res 12:(supplement 1);P226A,1997. (Poster presentation, 19th annual meeting of the American Society for Bone and MineraI Research, 1997, Cincinnati, OH).
 
Puzas JE, Lewis G, Hsu J. Reynolds PR, Rosier RN, O'Keefe RJ, Hicks DG, Cushing J, Martinez
DA. J Bone Min Res 12:(supplement 1); S241A,1997. (Poster presentation, 19th annual
meeting of the American Society for Bone and MineraI Research, 1997, Cincinnati OH).
 
Hicks DG, Fulmer C, O'Keefe RJ, Rosier RN, Teot LA, Puzas JE. Lead causes alterations in
growth plate architecture and matrix protein expression in an in vivo animal model. I Bone Min Res 12:(supplement 1); S296A, 1997. (Poster presentation, 19th annual meeting of the American Society for Bone and Mineral Research, 1997, Cincinnati OH).
 
 
 
 
Hsu JC, Bukata SV, Pollice PF, Puzas JE, Reynolds PR, Rosier RN, Hicks DG, Stroyer BF,
O'Keefe RJ. Paracrine induction ofinterleukin-10 in the pathologic periprosthetic bone resorption of aseptic loosening. J Bone Min Res 12:(supplement 1);S341A,1997. (Poster presentation, 19th annual meeting of the American Society for Bone and Mineral Research, 1997, Cincinnati OH).
 
D'Souza M, O'Keefe RJ, Reynolds PR, Gunter TE, Gunter KK, Puzas JE, Zuscik MI, Hicks DG,
and Rosier RN. Steady-State intracellular calcium levels control chondrocyte phenotype. Trans Orthop Res Soc 23:60A, 1998. (Platform presentation by Dr. Rosier, 1998 Orthopaedic Research Society Annual Meeting, New Orleans, LA).
 
Hsu JC, Bukata SV, Lewis GD, Hicks DG, Puzas JE, and O'Keefe RJ. Paracrine induction of interleukin-10 in periprosthetic osteolysis. Trans Orthop Res Soc 23: 125A, 1998. (Platform presentation by Dr. Hsu, 1998 Orthopaedic Research Society Annual Meeting, New Orleans, LA).
 
Hicks DG, O'Keefe RI, D'Souza M, Puzas JE, Teot LA, Reynolds PR, and Rosier RN.
Inappropriate expression of chondrocyte maturational pathways in osteoarthritis. Trans Orthop Res Soc 23:128A,1998. (Platform presentation by Dr. Hicks, 1998 Orthopaedic Research Society Annual Meeting, New Orleans, LA).
 
Lewis GD, Hsu JC, Zotalis G, Hicks DG, Rosier RN, O'Keefe RJ, Reynolds PR, Wu G, Messing
EM, and Puzas JE. In Vitro characterization of prostate metastases to bone. Trans Orthop Res Soc 23:161A,1998. (Platform presentation, 1998 Orthopaedic Research Society Annual Meeting, New Orleans, LA).
 
Hicks DG, Fulmer C, O'Keefe RJ, Rosier RN, Teot LA, and Puzas JE. Alteration in growth plate
architecture, autocrine regulation, and matrix protein expression in an in vivo animal model of lead intoxication. Trans Orthop Res Soc 23:450A, 1998. (Poster presentation, 1998
Orthopaedic Research Society Annual Meeting, New Orleans, LA).
 
Hicks DG, O'Keefe Rl, Teot LA, Constine LS, Puzas JE, Reynolds PR, and Rosier RN.
Molecular mechanisms in radiation injury to the growth plate: suppression of autocrine mitogenic stimuli. Trans Orthop Res Soc 23:507A,1998. (Poster presentation, 1998 Orthopaedic Research Society Annual Meeting, New Orleans, LA).
 
Wang AR, Zotalis G, Teot LA, O'Keefe RJ, McGary CT, Rosier RN, Hicks DG.
Dedifferentiated chondrosarcoma: An immunohistochemical study. Lab Invest 1998: 77: (poster presentation at the 87th Annual Meeting of the United States and
Canadian Academy of Pathology, Boston, MA, March 1998).
 
Zotalis G, Lewis GO, Teot LA, Hicks DG, Hsu J, O' Keefe RJ, Rosier RN, Messing EM,
Puzas JE. In vitro characterization of interactions of prostate cancer cell lines with bone: A
potential model for bone metastasis. Lab Invest 1998: 77: (poster presentation at the 87th Annual Meeting of the United States and Canadian Academy of Pathology, Boston, MA, March 1998).
 
Hicks DG, Goldblum JR, Patel R, Seo IS, Min Kw.  Reactive subserosal spindle cell proliferations:
An immunohistochemical study.  Lab Invest 82:16A;2002. (platform presentation at the Annual Meeting of the United States and Canadian Academy of Pathology, March 2002).
 
 
 
Tubbs RR, Skacel M, Pettay JD, Powell RD, Myles JL, Sreenan JJ, Hicks DG, Stoler MH, Roche
PC, Jenkins RB.  Interobserver reproducibility of a first generation autometallographic bright field assay for Her-2/neu amplification (GOLDFISH).  Lab Invest 82:54A;2002. (poster presentation at the Annual Meeting of the United States and Canadian Academy of Pathology, March 2002).
 
Chiesa-Vottero AG, Castilla EA, Borden E, Hartke M, Hicks DG, Tubbs RR, Goldblum JR.
Epidermal growth factor receptor (MPNST): An immunohistochemical and fluorescence in-situ hybridization (FISH) analysis.  Mod Pathol 16:29A; 2003. (poster presentation at the Annual Meeting of the United States and Canadian Academy of Pathology, March 2003).
 
Lin L, Hicks DG, Sigel JE, Bergfeld WF, Montgomery E, Fisher C, Tubbs RR, Skacel M, Hartke
M, Goldblum JR.  Fluorescence in-situ hybridization (FISH) analysis of cyclin D1 gene amplification in epithelioid sarcoma. Mod Pathol 16:57A; 2003. (poster presentation at the Annual Meeting of the United States and Canadian Academy of Pathology, March 2003).
 
Tubbs R Pettay J, Skacel M, Hicks D, Mele J, Powell R, Chen T, Nita H, Grogan T, Hainfeld J.
Automated chromogenic in-situ hybridization (CISH) for detection of HER2 gene amplification. Mod Pathol 16:212A; 2003. (poster presentation at the Annual Meeting of the United States and Canadian Academy of Pathology, March 2003).
 
Tash JE, Hicks DG, Tubbs RR, Skacel M, Pettay JD, Gurova K, Krivovrysenko V, Feinstein E,
Brainard JA, Gudkov A.  Discovery of new markers of prostate cancer (PCA) among the genes under negative control of tumor suppressors (TSG) using a combination of gene expression profiling (EP) and chromogenic in-situ RNA hybridization (CISH) on tissue microarrays (TMA). Mod Pathol 16:785A; 2003. (poster presentation at the Annual Meeting of the United States and Canadian Academy of Pathology, March 2003).
 
Yoder BJ, Hicks DG, Pettay J, Mele J, Skacel M, Tubbs RR.  Investigation of oncogenic viruses
utilizing in-situ hybridization in different nasopharyngeal carcinoma subtypes.  Mod Pathol 16:1017A; 2003. (poster presentation at the Annual Meeting of the United States and Canadian Academy of Pathology, March 2003).
 
Kandil DH, Skacel M, Liu WW, Pettay JD, Goldblum JR, Hicks DG, Tubbs RR.  Liquid based thin
layer preparation (ThinPrep) from archival frozen tissue (FT): An alternative for fluorescence in-situ hybridization (FISH).  Mod Pathol 16:1482A; 2003. (poster presentation at the Annual Meeting of the United States and Canadian Academy of Pathology, March 2003).
 
Shao YY, Wang L, Hicks DG, and Ballock RT.  Using Laser Capture Microdissection to examine
gene expression in functionally distinct populations of growth plate chondrocytes.  (Poster presentation, American Society for Bone and Mineral Research, annual meeting, 2003).
 
Willis-Eppinger G, His E, Hicks DG.  Automated instrumentation in
immunohistochemistry (IHC): improvements in efficiency and turnaround time.  (Poster presentation for the National Society of Histotechnology annual meeting, 2003).
 
Safran O, Derwin KA, Powell K, Ilaslan H, Hicks DG, Iannotti JP.  Rotator cuff muscle atrophy
and passive tissue tension after chronic detachment in a canine model.  (Platform presentation, Orthopaedic Research Society annual meeting, 2003).
 
 
 
Tubbs R, Pettay J, Powell R, Mele J, Downs-Kelly E, Hicks D, Hainfeld J. Enzyme Metallography (EnzMetÔ): A Novel Second Generation Bright Field Assay for Detection of HER2 Gene Amplification in Breast Carcinoma. Presented at the Association of Molecular Pathology, Orlando, November 19-21, 2003. J Molec Diag 5:270, 2003.
 
Hicks D, Ruddy T, Downs-Kelly E, Borthwick D, Pettay J, Powell R, Hainfeld J, Budd T, Tubbs R.  Quantitative Image Analysis of GOLDFISH; A 1st Generation Gold Facilitated Autometallographic Bright Field In Situ Hybridization Assay For HER2 Gene Amplification In Invasive Breast Cancer.  Presented at the 26th Annual San Antonio Breast Cancer Symposium, December 3-6, 2003 and published in the Special Issue of the Breast Cancer Research and Treatment, Vol. 82, Supplement 1, pS145, 2003
.
Hicks, D, McDonald L, Kotschi H, Skacel M, Tubbs RR.  Design, construction, and preliminary validation of tissue midi-arrays (TDMA's).  Presented at the National Society of Histotechnology Annual Meeting in Louisville, KY, October 18-23, 2003.
 
D Hicks, M Skacel, E Downs-Kelly, M Cheang, J Pettay, F D Hsu, T O Nielson, J Mele, D G
Huntsman, R Powell, J Hainfeld, T Grogan and R Tubbs. SILVERFISH-A Novel Bright Field Assay for Simultaneous Detection of HER2 Gene Amplification and Protein Expression Predicts Clinical Outcome in Invasive Breast Cancer. Presented at the United States and Candian Academy of Pathology Annual Meeting; Vancouver, March 6-12, 2004. Lab Invest, 84:34A, 2004 and Mod Pathol 17:34A, 2004.
 
D G Hicks, A G Chiesa, E Borden, M Hartke, R R Tubbs, S Tarr, J R Goldblum. Epidermal
Growth Factor Receptor (EGFR) expression in Synovial Sarcoma (SS): An immunohistochemical (IHC), Fluorescence In Situ Hybridization (FISH), and Quantitative image analysis study..  Presented at the United States and Candian Academy of Pathology Annual Meeting; ; Vancouver, March 6-12, 2004.  Lab Invest 84:15A, 2004 and Mod Pathol 17:15A, 2004.
 
E Downs-Kelly, M Stoler, R Tubbs, M Skacel, T Grogan and D G Hicks. The Influence of
Polysomy 17 (CEP17+) on HER2 Protein Expression in Carcinoma of the Breast..  Presented at the United States and Candian Academy of Pathology Annual Meeting; ; Vancouver, March 6-12, 2004.  Lab Invest 84:29A, 2004 and Mod Pathol 17:29A, 2004.
 
J Fine, E Downs-Kelly, D G Hicks, J Pettay, S Tarr, T Ruddy R Powell, J Mele, J Hainfield, T
Grogan, M Skacel,  D Borthwick, and R Tubbs. High-throughput image analysis of HER2 gene amplification detected by second-generation gold-facilitated autometallographic bright field in-situ hybridization assay (GOLDFISH). Presented at the United States and Candian Academy of Pathology Annual Meeting; Vancouver, March 6-12, 2004.. Lab Invest 84:355A, 2004 and Mod Pathol 17:355A, 2004.
 
D G Hicks, M Skacel, G T Budd,  M Hartke, J Pettay, and R R Tubbs. Incidence of Topoisomerase II-alpha (TOP2A) Co-amplification and Deletion of Adenocarcinoma of the Breast with HER2 Gene Amplification.   Presented at the United States and Candian Academy of Pathology Annual Meeting; ; Vancouver, March 6-12, 2004.  Lab Invest 84:34A, 2004 and Mod Pathol 17:34A, 2004.
 
 
 
 
 
R Tubbs, J Pettay, M Skacel, E Downs-Kelly, D Hicks, R Powell, P Roche, T Grogan, J Mele and J  Hainfeld. Analytical Validation of SILVERFISH, a Bright Field Second Generation Autometallographic Assay for Concomitant Detection of HER2 Gene Amplification and Encoded Protein Expression.   Presented at the United States and Candian Academy of Pathology Annual Meeting; ; Vancouver, March 6-12, 2004.  Lab Invest 84:52A, 2004 and Mod Pathol 17:52A, 2004.
 
Yoder BJ, Tso E, Skacel M, Choueiri T, Tarr S, Budd T, Tubbs RR, Adams J, Dawson AE, Hicks DG.  The Expression of Fascin, an Actin Bunding Motiity-Associatd Protein in Breast Cancer. Presented at the United States and Candian Academy of Pathology Annual Meeting; Vancouver, March 6-12, 2004.  Lab Invest 84:54A, and Mod Pathol 17:54A, 2004.
 
Liu WW, Skacel M, Hicks DG, Trupiano JK, Tubbs RR, Goldblum JR.  Initial Experience with a Novel Fluorescence In Situ Hybridization (FISH) Assay for Detection of Ewing’s Sarcoma (EWS) Gene (22q12) Translocation in Paraffin-Embedded Tissue. Presented at the United States and Candian Academy of Pathology Annual Meeting; Vancouver, March 6-12, 2004.  Lab Invest 84:358A, and Mod Pathol 17:358A, 2004.<, /D, IV,>
 
Hicks D, Skacel M, Downs-Kelly E, Cheang M, Pettay J, Hsu FD, Nielsen TO, Mele J, Huntsman DG, Powell R, Hainfeld J, Grogan T, Tubbs R.  Invasive Breast Cancer Clinical Outcomes is Predicted by a Novel Bright-Field Assay for the Simultaneous Detection of HER2 Gene Amplification and Protein Expression (SILVERFISH).  Presented at the American Society of Clinical Oncology (ASCO) Annual Meeting in New Orleans, LA, June 5-8, 2004.  J Clin Oncol 22:435.
 
Budd, GT, Tso, E, Yoder, B, Choueiri, T, Elson, P, Tarr, S, Skacel, M, Tubbs, R, Dawson, A, Hicks, D.  Using Novel Protein Antibodies on Tissue Microarrays (TMAs) for Breast Cancer Prognostication. Proc Am Soc Clin Oncol 23:863, 2004.  J Clin Oncol 22:8665.
 
Tarr SM, Short S, Hansen K, Morken T, Xia H, Downs-Kelly E, Tubbs R, Hicks D. Evaluation of a New Rabbit Monoclonal Antibody (SP3) against HER2 in Adenocarcinoma of the Breast; and Immunohistochemical (IHC) Study.  Presented at the Association for Molecular Pathology, Huntington Beach, November 11-14, 2004.  J Molec Diag 6(4):439.
 
Pettay J, Powell R, Hainfeld J, Hicks D, Roche P, Powell W, Grogan T, Tubbs R.  High Resolution Immunophenotyping of Subcellular Compartments by Enzyme Metallography using Tissue Microarrays (TMA).  Presented at the Association for Molecular Pathology, Huntington Beach, November 11-14, 2004.  J Molec Diag 6(4):434.
 
Budd GT, Yoder BJ, Tarr SM, Tso E, Choeiri T, Tubbs RR, Crowe J, Short S, Ruddy T, Morken T, Hicks DG.  Comparison of ER and PR Determination by Pathologists vs An Image Analysis System.  Presented at the San Antonio Breast Cancer Symposium, December 8-11, 2004.  Br Can Res Treat 88:S55, Supplement 1, 2004.
 
Tarr SM, Downs-Kelly E,  Apte-Anand B, Yoder BJ, Skacel M, Gessner D, Tubbs RR, Hicks DG.  Overexpression of Tissue Inhibitor of Metalloproteinases-3 (TIMP-3) in Invasive Carcinoma of the Breast:  an (IHC) Immunohistochemical Study.  Presented at the San Antonio Breast Cancer Symposium, December 8-11, 2004.  Br Can Res Treat 88:S120, Supplement 1, 2004.
 
 
 
Yoder BJ, Pettay J, Tarr SM, Ruddy T, Tso E, Budd T, Adams J, Tubbs RR, Crowe JP, Chouieri T, Hicks DG.  Fascin Expression Correlates with Hormone Receptor Negative Breast Cancers and a More Aggressive Clinical Course:  An Immunohistochemical (IHC) and Image Analysis Study.  Presented at the San Antonio Breast Cancer Symposium, December 8-11, 2004.  Br Can Res Treat 88:S119, Supplement 1, 2004.
 
Choeiri T, Yoder BJ, Tso E, Budd GT, Elson P, Tarr SM, Tubbs RR, Morken T, Hicks DG.  Comparison or Rabbit and Murine Monoclonal Antibodies for Immunohistochemical Analysis of ER and PR.  Presented at the San Antonio Breast Cancer Symposium, December 8-11, 2004.  Br Can Res Treat 88:S194, Supplement 1, 2004.
 
Tubbs R, Pettay J, Downs-kelly E, Skacel M, Myles J, Powell R, Hainfeld J, Roche P, Grogan T, Sreenan JJ, Hicks D.  Interobserver Reproducibility of Silverfish, A Bright Field Second Generation Metallographic Assay for Concomitant Detection of HER2 Gene Amplification and Encoded Protein Expression.  Presented at the San Antonio Breast Cancer Symposium, December 8-11, 2004.  Br Can Res Treat 88:S194, Supplement 1, 2004.
 
Hicks DG, Tarr SM, Ruddy T, Skacel M, Downs-Kelly E, Yoder BJ, Tso E, Budd T, Crowe J, Choeiri T, Tubbs RR.  Expression of a Cytoskeletal Focal Adhesion Protein Paxillin, in Breast Cancer:  An Immunohistochemistry (IHC) and Image Analysis Study.  Presented at the San Antonio Breast Cancer Symposium, December 8-11, 2004.  Br Can Res Treat 88:S121, Supplement 1, 2004.
 
Downs-Kelly E, Patel RM, Goldblum JR, Weiss SW, Folpe AL, Tubbs RR, Hicks DG, Skacel M.  The Utility of Novel Fluorescence In-Situ Hybridization (FISH) Probes in the Diagnosis of Myxoid Soft Tissue Neoplasms.  Presented at the US-Canadian Academy of Pathology, San Antonio, February 26-March 4, 2005.  Lab Invest 85:13A,2005.
 
Lin L, Xu B, Pettay J, Bergfeld WF, Skacel M, Hicks D, Tubbs RR, Goldblum JR.  Amplification of CDK4 and MDM2 Genes in Epithelioid Sarcomas Detected by Array-Based Comparative Genomic Hybridization and Fluorescence In Situ Hybridzation.  Presented at the US-Canadian Academy of Pathology, San Antonio, February 26-March 4, 2005.  Lab Invest 85:17A,2005.
 
Yoder BJ, Skacel M, Choueiri T, Gaile DP, Conroy J, Nowak N, Pettay J, Crowe JP, Crownover RL, Budd T, Tubbs RR, Hicks DG.  Genomic Alterations in the Progression of Stage 2 Breast Carcinoma:  An Array-Based Comparative Genomic Hybridization (A-CGH) Study.  Presented at the US-Canadian Academy of Pathology, San Antonio, February 26-March 4, 2005.  Lab Invest 85:56A,2005.
 
Yoder BJ, Choueiri T, Downs-Kelly E, Skacel M, Hainfeld J, Powell R, Roche P, Grogan T, Pettay J, Budd T, Hicks DG, Tubbs RR.  EnzMet GenePro, a Novel Bright Field Assay that Simultaneously Profiles HER2 Genotype and Phenotype, Correlates with Overall and Disease Free Survival of Breast Cancer.  Presented at the US-Canadian Academy of Pathology, San Antonio, February 26-March 4, 2005.  Lab Invest 85:56A,2005.
 
Tubbs RR, Swain E, Pettay J, Hartke M, Keslar K, Simmerman K, Bronner MP, Hicks D, Crowe J, Skacel M.  An Approach to High Throughput Automated Multi-Color FISH Scanning of Tissue Microarrays.  Presented at the US-Canadian Academy of Pathology, San Antonio, February 26-March 4, 2005.  Lab Invest 85:335A,2005.
 
 
 
Yang B, Roma AA, Yoder BJ, Tarr S, Tso E, Choueiri T, Budd T, Crowe JP, Hicks DG.  Loss of
14-3-3 sigma expression associates with favorable prognosis in breast carcinoma. 2005 USCAP, Presented at the US-Canadian Academy of Pathology, San Antonio, February 26-March 4, 2005.  Mod Pathol. 18:245A,2005.
 
 
National Workshops and Invited Presentations:
 
Faculty: Orthopedic Pathology Review Course.
Harry Schwamm, M.D., Course Director, Atlantic City, NJ. Newport Beach. CA. and
Philadelphia. P A. 1989-1996. (Sponsored by the Departments of Pathology and
Orthopaedics, The Graduate Hospital. Philadelphia. PA).
 
Faculty: Workshop on: In situ Hybridization: Non-radioactive in situ hybridization using digoxigenin labeled oligonucleotide probes: application to musculoskeletal tissues. Presented at the New York State Histotechnological Society Annual Meeting and Seminar. Buffalo. NY, April 1993.
 
Guest faculty: Symposium on: Diagnosis and management of musculoskeletal neoplasms. Harry
Schwamm, M.D.. Course Director. Philadelphia PA, April 1993 (Sponsored by the
Departments of Pathology and Orthopaedics, The Graduate Hospital. Philadelphia. PA).
 
Guest speaker: The effects of lead on bone structure and function. Presented at the Workshop on
Skeletal Lead. NIEHS, Research Triangle Park, NC, September 27-28, 1993. (Sponsored by the National Institute of Environmental Health Sciences and the Carnegie Foundation).
 
Faculty: Workshop on: Non-decalcified plastic embedded sectioning of skeletal tissue in the      evaluation of metabolic bone disease and other skeletal disorders: clinical, biologic, and       technical considerations. Presented at the New York State Histotechnological Society   Annual Meeting and Seminar, Albany, NY, April 1994.
 
Guest speaker: Non-neoplastic diseases of the skeleton: Metabolic bone disease and osteoporosis, fractures, and osteomyelitis. Millard Fillmore Health System, Department of Pathology, C.M.E meeting, October 10, 1995.
 
Guest speaker: The interaction of tumor cells with the bone environment: lessons from small round
       blue cells. Presentation to the Western New York Society of Pathologists, Buffalo, NY        January 24, 1996.
 
Guest speaker: The role of the bone biopsy in the evaluation of osteoporosis. Osteoporosis for the primary care physician. Rochester Academy of Medicine, Rochester, NY, April 19, 1996.
 
Faculty: Workshop on: Cytopathology of bone and soft tissue lesions: An integrated approach to
differential diagnosis. American Society of Clinical Pathologists Fall Meeting, San Diego, CA, October 2, 1996.
 
Co-Director: Workshop on: Nonradioactive in situ hybridization using oligonucleotide probes:
Research and clinical applications, National Society for Histotechnology Annual Meeting,
Albuquerque, NM, October 21, 1996.
 
 
 
Invited lecture: "Pathology, new technologies, new directions, the next 75 years: The role of anatomic pathology in the rapidly expanding area of molecular and nucleic acid therapeutics. Address to the Advisory Council, American Society of Clinical Pathologists, Spring Meeting, Chicago, IL, April 6, 1997.
 
Faculty: Workshop on: Cytopathology of bone and soft tissue lesions: An integrated approach to
differential diagnosis. American Society of Cytopathology 45th Annual Meeting,
Boston, MA, November 8, 1997.
 
Invited lecture: "Cytopathology of bone: An integrated approach to differential diagnosis."
Western New York Society of Pathologists, Buffalo, New York, November 19, 1997.
 
Invited lecture: "The Pathology of Joint Disease." Department of Pathology, State University of New York at Buffalo, Buffalo General Hospital, Buffalo, New York, November 19, 1997.
 
Guest speaker: What is the value of a bone biopsy in the evaluation of a patient with osteoporosis? : Basic and Advanced Principles in the care of the osteoporotic patient. Marriott-Airport Hotel, Rochester, NY, Apri118, 1998, Sponsored by the University of Rochester School of Medicine and Dentistry Office of Continuing Professional Education.
 
Guest speaker: Skeletal pigmentation as a result of medications and metabolic diseases.
Cleveland Society of Pathology.  February, 2002.
 
Guest speaker: Automated In-situ Hybridization and Gene Expression Profiling: An Update. 
Society for Applied Immunohistochemistry, Quarterly Meeting, Memorial Sloan-Kettering Cancer Center, New York, New York, July 17, 2002.
 
Guest speaker: Automated In-situ Hybridization: A tool for gene discovery.  International Society
for Analytical and Molecular Morphology, Annual Meeting, Santa Fe New Mexico, September 15-19, 2002.
 
Faculty, workshop presentation: Immunohistochemistry and the critical evaluation of controls. 
Presented at the 28th annual National Society for Histotechnology Symposium, Long Beach, California, September 28- October 3, 2002.
 
Invited seminar speaker: The molecular mechanisms of skeletal metastatic disease and the
disruption of normal bone remodeling.  Genentech BioOncology, San Francisco California, October 16th, 2002.
 
Participant, Pathology Advisory Board Meeting for, Genentech BioOncology, the Claremont
Resort, Berkeley, California, October 16-18, 2002.
 
Invited seminar speaker: Prognostic markers in breast cancer management.  As part of, Molecular
Diagnosis in Women’s Health; an Educational Forum.  New England Medical Center, Boston Mass, October 22, 2002.
 
Invited seminar speaker: Prognostic markers in breast cancer management.  As part of, Molecular
Diagnosis in Women’s Health; an Educational Forum.  Stanford University Medical Center, Palo Alto California , November 1, 2002.
 
Invited seminar speaker: Prognostic markers in breast cancer management. As part of, Molecular
Diagnosis in Women’s Health; an Educational Forum for Pathologists, Magee Women’s Hospital of UPMC Health System, Pittsburgh PA, January 2003.
Invited seminar speaker:  Prognostic markers in the evaluation of breast cancer: The role of the
pathologist. Eastern Great Lakes Pathology, X-Cell Laboratories of Western New York, Buffalo New York, March 2003.
 
Invited Presentator: Pathology Grand Rounds. Molecular Mechanisms Mediating Metastasis to the Musculoskeletal system.  University Hospitals of Cleveland, Institute of Pathology,
            Cleveland OH, March 2003.
 
Moderator:  Platform session, Bone and soft tissue.  Annual Meeting of the United States and
      Canadian Academy of Pathology, March 2003.
 
Invited seminar speaker: Tissue based studies of gene expression: The utility of automated ISH
and TMA’s in gene discovery and clinical validation.  University of Minnesota, Cytogenetics, Molecular Diagnostics, Lab Med, and Surgical Pathology. Minneapolis MN, April 2003.
 
Workshop:  Resident Review Course. Bone Pathology: An integrated approach to diagnosis.
American Society for Clinical Pathology, Hoffman Estates, Chicago IL, April 2003.
 
Seminar speaker: University of Miami. Prognostic markers in the evaluation of breast cancer: HER2 status and the role of the pathologist in determining therapy, July 31- August 1, 2003.
 
Pathology Resident Seminar: University of Miami.  An Integrated Approach to the Differential
            Diagnosis of Skeletal Pathology, July 31 - August 1, 2003.
 
Lecturer: ASCP Teleconference. An Integrated Approach to Differential Diagnosis.  Fall 2003
           Teleconferences Series. Pathology of Bone Lesions: An Integrated Approach to Differential
            Diagnosis, September 26, 2003
 
Presentation/Symposium: International Society for Analytical & Molecular Morphology. LaFonda
            Hotel, Sante Fe NM.  Tissue Based Gene Expression Analysis: Validation of Expression
            Arrays via Automated RISH and TMAs.  October 13 - October 17, 2003.
 
Presentation/Symposium: National Society of Histotechnologists. Louisville Kentucky
Immunohistochemical controls: Critical Evaluation of Staining Characteristics; Critical
Evaluation of Staining Characteristics. October 19 - October 21, 2003.
 
Presentation/Symposium: National Society of Histotechnologists. Louisville Kentucky. Design,
Construction and Preliminary Validation of Tissue Midi-Arrays. October 19 - October 21, 2003.
 
Speaker: Ohio Society of pathology.  Columbus Ohio. Prognostic and Predictive Markers in the
Diagnosis and Management of Breast Cancer: The Role of the Pathologist. October 25, 2003
 
Speaker: Molecular Discovery Systems. Advances and Strategies in Molecular Pathology and
Target Discovery. Boston Marriott Cambridge, Cambridge MA  In-Situ Hybridization in the Pathology Laboratory: General Principles, Automation, and Emerging Research Applications for Tissue Based Studies of Gene Expression.  November 4, 2003
 
 
 
Guest speaker: Technology Premiere. Waldorf, Astoria, New York.  New developments in the
Detection of Over-expression of the HER2 gene, and it Implication for the Diagnosis and Management of Breast Cancer. November 17 - November 18, 2003.
 
Seminar: Advanced Pathology Services. Meritcare Health Systems. Path-to-Path Session.  Fargo
      ND. November 23 - November 24, 2003.
 
Seminar: 26th Annual San Antonio Breast Cancer Symposium. . Henry B Gonzalez Convention
Center, San Antonio.  Quantitative image and analysis of Goldfish a first generation
gold-facilitated autometallographic bright field in-situ hybridization assay) for HER2 gene
amplification in invasive breast cancer.  December 1 - December 4, 2003.
 
Speaker: Roche Diagnostics Summit. Pleasanton CA. Molecular Staging of breast cancer: Gene
           expression via Arrays and FISH.  December 9, 2003 - December 11, 2003.
 
Cuyahoga County, Board of Health, Educational Seminar, Cleveland OH.  Osteoporosis:  Factors
Affecting Bone Loss in the Female Population and the Importance of Screening.  February
11, 2004.
 
Invited Seminar Speaker: San Diego Symposium. Advances and Strategies in Molecular Pathology and Target Discovery.  Tissue Micro-arrays, a Powerful Tool for Cost Effective Molecular Genetic Profiling of Clinical Samples.  February 18 - February 22, 2004.
 
2004 Oncotype DXtm Summit Meeting.  Participant in Diagnostic Breast Cancer Summit,
Sponsored by Genomics Health Incorporated. The Fairmont Hotel, San Francisco, California. February 27 - February 28, 2004.
 
Lecturer: American Society for Investigative Pathology (ASIP) Experimental Biology 2004, (in
conjunction with International Society of Molecular Morphology), Annual Meeting. Trends in Experimental Pathology: Frontiers in Molecular Morphology Translational Research. Molecular topography of gene expression: automated RNA in-situ hybridization of tissue micro-arrays as a validation tool for cDNA array--derived expression profiles in prostatic adenocarcinoma. , Washington DC. April 17 - April 19, 2004.
 
ASCP Resident Review Course. Bone Pathology. AmeriSuites, Hoffman Estates, IL. Pathology of
      Bone Lesions: An Integrated Approach to Differential Diagnosis. Apri, l 2, 6 - April 27, 2004.
 
Invited Speaker: 2004 Executive War College (The Dark Group). Astor Crowne  Plaza, New
Orleans LA.  Harvesting major gains in histology and anatomic pathology: The Cleveland Clinic Experience.  April 27 - April 29, 2004.
 
Invited Speaker: Minnesota Society for Histotechnologists, Iowa Society of Histotechnology,
Wisconsin Histology Society.  The Development of Tissue Micro-arrays as a Translation Research Tool in Pathology Laboratories. April 30, 2004
 
Maryland Society for Histotechnology. "Chromogenic In-situ hybridization, its Emergence
 as a New Technology for Assessing Gene Expression in Tissue Sections".  June 2004.
 
Invited Speaker, Colorado Society of  Clinical Pathology. "Molecular Genetic Markers in the
Diagnosis and Management of Breast Cancer: An Update and Review of Recent Advances".  Vail Colorado, July 9, 2004.
 
 
Session Chairman and Invited Speaker: Symposium on Advances in Molecular Pathology; Target
and Biomarker Discovery and Validation.  "Tissue Microarrays: A Powerful Tool for Cost-Effective Molecular Genetic Profiling of Clinical Samples".  Research Triangle Park, Durham, NC, July 15,2004.
 
Saint Mary Medical Center, Duluth Minnesota, Invited Speaker: "The Evaluation of HER2 Status
in the Clinical Laboratory, a Workshop and Update for Pathologist", Aug 29th 2004.
 
Invited Speaker: Symposium on Advances in Molecular Pathology; Target and Biomarker
Discovery and Validation.  "Tissue Microarrays: A Powerful Tool for the Clinical Validation of  New Biomarkers in Oncology".  Research Triangle Park, Durham, NC, July 15,2004.
 
Faculty and Invited Speaker, Cleveland Clinic Foundation Genomic Medicine Course: "Genomics
and the Developing Role of Molecular Pathology in the Diagnosis of Cancer". Lerner Research Institute, Cleveland Ohio, Fall, 2004.
 
Faculty and Invited Speaker, Cleveland Clinic Foundation Breast Cancer Summit: "An Introduction
to the Genomics of Breast Cancer for the Practicing Physician.  Intercontinential Hotel and Conference Center, Cleveland Ohio, October 8th, 2004.
 
Invited Speaker, Swedish Covenant Hospital Tumor Board: "Prognostic and Predictive Markers in
the Diagnosis and the Therapeutic Decision Making in Breast Cancer".  Chicago, IL, November 28th, 2004.
 
Invited Speaker and Panel Member, Educational Symposium at the San Antonio Breast Cancer
Symposium: "The Development of Genomic Testing in the Diagnosis and Management of Breast Cancer: The Role of the Pathologist".  San Antonio Breast Cancer Symposium, San Antonio TX, December 2004.
 
Invited Speaker and Faculty, Breast Cancer Oncotype Dx Summit: An Introduction to the
Developing Role of Genomics in the Diagnosis of Breast Cancer".  Phoenix, AZ, January 2005.
 
Invited Speaker and Faculty, The Tucson Symposium on New Developments in Cell Signaling:
"Tissue Microarrays as Tools for the Study of Signaling Pathways in Clinical Tissue Samples and Biomarker Development".  Sponsored by Ventana Medical Systems, Tucson AZ, March 2005.
 
Invited Speaker and Panel Member, International Society of Breast Pathology, Evening
Subspecialty Conference: "Fibroepithelial Lesions of the Breast: Morphologic Diversity and New Molecular Developments".  United States and Canadian Academy of Pathology Annual Meeting, March, 2005, San Antonio TX.
 
Invited Speaker, 1st Annual Women's Health Summit at the Cleveland Clinic Foundation:
"Molecular Profiling in Breast Cancer, Implications for Patient Management" Intercontinental Hotel and Conference Center, Cleveland Ohio, April, 2005.
 
Visiting Faculty and Seminar Speaker, University of Pittsburgh, Department of Pathology and
Laboratory Medicine: "Cytoskeletal Proteins as Potential New Prognostic and Predictive Markers in Breast Cancer". Pitsburgh PA, April, 2005.
 
 
 
Invited Speaker, Mahoning County Breast Cancer Support Group, Surviors Working for a Cure,
Dinner Program: What New In the Diagnosis of Breast Cancer and the Developing Role of Genomics in the Care of the Newly Diagnosed Patient". Boardman Ohio, May, 2005.
 
Faculty Member and Invited Speaker, ASCP Resident Review Course: "Orthopaedic Pathology: An Integrated Approach to the Differential Diagnosis of an Orthopaedic Lesion".  Chicago IL, May, 2005.
 
Invited Speaker, New York State Society of Pathologists Annual Continuing Medical Education
Meeting: "New and Emerging Prognostic Marker and Molecular Approaches to the Diagnosis of Breast Cancer".  Albany NY, May, 2005.
 
USCAP Annual Meeting, February, 2006, Atlanta, GA; Platform presentation-Breast Cancers with
Brain Metastases are more likely to be Estrogen Receptor Negative, Express the Basal Cytokeratin CK5/6 and Over-express HER2 and EGFR; DG Hicks, et al. and Poster-“Ezrin, a Cytoskeletal Linker Protein is Expressed in a Subset of Breast Cancers and Correlates with Estrogen Receptor Expression and a More Favorable Clinical Outcome.
 
Guest Speaker, University of Tennessee, “The Evolving Role of Biomarkers and Genomics in the
Diagnosis and Therapeutic Management of Breast Cancer.”
February 21 and 22, 2006
 
CALGB Spring Committee Meeting, Chicago, Illinois, Breast Committee, Pathology Committee,
and Breast Solid Tumor Correlative Sciences Working Group, March 2006
 
AJCC Grant Review Panel, Review grants submitted in response to the AJCC’s request for
proposals entitled, “Improving AJCC/UICC TNM Cancer Staging:  Developing and Validating New Algorithms for Cancer Prognosis, Staging, and Predicting Response to Therapy.” Chicago, Illinois, March 2006
 
ASCP Faculty, Resident Review Course-Anatomic Pathology, "Orthopaedic Pathology: An
Integrated Approach to the Differential Diagnosis of an Orthopaedic Lesion".  Northern Illinois University, April 2006
 
Genentech Integrated Education Speakers Bureau Development Meeting, New York, NY, April
2006
 
Program Chair, Herceptin Diagnostics Advisory Board Meeting, New York, NY, October 2006
 
Invited Speaker/Faculty Member for Herceptin-supported program on HER2-Positive Metastatic
Breast Cancer Diagnostic Tools and Challenges, Indianapolis, IN, July 2006
 
Invited Consensus Conference Facilitator, Standardization of IHC to Improve Quality, Consistency
and Reliability, sponsored by Dako North America, Inc., Santa Barbara, CA, August 2006
 
CAP 2006 Annual Meeting, San Diego, CA, Workshop presented in conjunction with Dr. Elizabeth
Hammond and Dr. Kenneth Bloom, “NCCN and ASCO Guidelines for HER2 Testing: What They Mean to You.”  September 2006
 
CAP 2006 Annual Meeting, San Diego, CA, Workshop presented in conjunction with Dr. Sunil
Badve and Dr. Rick Baehner, “Molecular Prognostication in Breast Cancer in the 21st Century:  An Introduction from Benchtop to Bedside.” September 2006
 
Invited Speaker, Genentech Integrated Education Speakers’ Bureau, “HER2 Positive Metastatic
Breast Cancer Diagnostic Tools and Challenges.” Toledo OH, Grand Blanc MI, and Southfield MI, September 2006
 
Invited Speaker, Genentech Integrated Education Speakers’ Bureau, “HER2-Positive Breast
Cancer: Diagnostic Tools and Challenges.” Williamsville, NY December 2006
 
Invited Consensus Conference Facilitator, Standardization of IHC to help Improve Prognostic and
Predictive Biomarker Assays, sponsored by Dako North America, Inc., Duck Key, FL, January 2007
 
Invited Speaker, Genentech Integrated Education Speakers’ Bureau, “HER2-Positive Node Positive Breast Cancer: Diagnostic Tools and Challenges.” Dearborn MI, Farmington Hills MI, Ann Arbor MI,  March 2007
 
USCAP Annual Meeting 2007, Faculty Member, Short Course entitled, “Breast Pathology in the
Molecular Era” San Diego, CA, March 2007
 
Invited Speaker/Moderator, USCAP Forum by Dako North America, Inc., entitled, “HER2
Guidelines and How They Are Changing the Paradigm.”  San Diego, CA, March, 2007
 
Invited Speaker, Genentech Integrated Education Speakers’ Bureau, “HER2-Positive Node Positive Breast Cancer: Diagnostic Tools and Challenges,” Williamsville, NY, March 2007.
 
Invited Speaker, Genentech Integrated Education Speakers’ Bureau, “HER2-Positive Node Positive Breast Cancer: Diagnostic Tools and Challenges, Akron OH, April 2007
 
Invited Speaker, Genentech Integrated Education Speakers’ Bureau, “Targeting HER2-Positive
Breast Cancer:  The Role of Herceptin,” Barberton, OH, May 2007
 
Visiting Professor at Fairview Hospital, Resident Research Recognition Day, Presenting
 “Molecular Genetic Profiling of Breast Cancer Clinical Samples:  Translating Basic Science Discoveries into New Tools for Diagnosis & Management” Cleveland, OH, June 2007
 
Invited Speaker, Genentech Integrated Education Speakers’ Bureau, “Targeting HER2-Positive
Breast Cancer:  The Role of Herceptin,” Twinsburg, OH, June 2007
 
Invited Speaker, Genentech Integrated Education Speakers’ Bureau, “Targeting HER2-Positive
Breast Cancer:  The Role of Herceptin,” Jamestown, NY, June 2007
 
Participant in Genentech Integrated Educational Speakers’ Bureau Development Meeting, Chicago, IL, June 2007
 
Invited Speaker, Genentech Integrated Education Speakers’ Bureau, “Targeting HER2-Positive
Breast Cancer:  The Role of Herceptin,” Buffalo, NY, June 2007
 
Invited Chair, Herceptin Pathology Advisory Board Meeting, sponsored by Genentech BioOncology, Chicago, IL, July 16-17, 2008.
 
Invited Speaker, Genentech National Sales Meeting, “Surgical Overview - How Testing and Surgery Impact Treatment Decisions”.  Washington, DC, September 16-17, 2008.
 
 
Invited Speaker, Genentech Meeting, “HER2-positive breast cancer: review of biologic relevance and optimal use of diagnostic tools”  Pittsburgh, PA, September 11-12, 2008
 
CAP 2008 Annual Meeting, San Diego, CA.  Workshop:  “The Indispensible Pathologist” with Dr. Nancy Cornish and Dr. Michael Laposata.  San Diego, CA. September 2008 -
 
CAP 2008 Annual Meeting, San Diego, CA.  Workshop:  “Fluorescence in situ Hybridization: Interpretation of HER2 Testing.” San Diego, CA. September 2008.-
 
 
 
Rev. 10/2008
DAVID G. HICKS(美国) 在本站 [网络讲堂] 讲授的课程列表
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